Novel magnetic micro-structured porous materials for biomedical applications
Novel, porous and dense, ceramic (Fe3O4 & Ca2Fe2O5) and glass-ceramic (phosphate-based glass matrix with magnetic domains) magnetic microspheres have been manufactured for the first time via a rapid, single-stage, flame spheroidisation process. Morphological, structural, and compositional invest...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2023
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| Online Access: | https://eprints.nottingham.ac.uk/73616/ |
| _version_ | 1848800796169207808 |
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| author | Molinar Diaz, Jesus |
| author_facet | Molinar Diaz, Jesus |
| author_sort | Molinar Diaz, Jesus |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Novel, porous and dense, ceramic (Fe3O4 & Ca2Fe2O5) and glass-ceramic (phosphate-based glass matrix with magnetic domains) magnetic microspheres have been manufactured for the first time via a rapid, single-stage, flame spheroidisation process. Morphological, structural, and compositional investigations provide evidence into the microsphere formation mechanisms, as a function of Fe3O4 precursor particle size, precursor-to-porogen mass ratio, and gas flow settings. Optimised conditions for the flame spheroidisation processing of these ceramic and glass-ceramic, porous and dense magnetic microspheres are identified. The magnetic properties of the materials provided for controlled induction heating to a constant level (40 – 45 °C), making these microspheres highly appropriate for localised magnetic hyperthermia applications. Complementary, cytocompatibility investigations confirmed the suitability of porous microspheres for biomedical applications. It is suggested that the flame-spheroidised materials developed opens up new opportunities for the rapid manufacture of innovative synergistic biomaterials, towards magnetic hyperthermia applications. |
| first_indexed | 2025-11-14T20:57:15Z |
| format | Thesis (University of Nottingham only) |
| id | nottingham-73616 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T20:57:15Z |
| publishDate | 2023 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-736162023-07-21T04:40:22Z https://eprints.nottingham.ac.uk/73616/ Novel magnetic micro-structured porous materials for biomedical applications Molinar Diaz, Jesus Novel, porous and dense, ceramic (Fe3O4 & Ca2Fe2O5) and glass-ceramic (phosphate-based glass matrix with magnetic domains) magnetic microspheres have been manufactured for the first time via a rapid, single-stage, flame spheroidisation process. Morphological, structural, and compositional investigations provide evidence into the microsphere formation mechanisms, as a function of Fe3O4 precursor particle size, precursor-to-porogen mass ratio, and gas flow settings. Optimised conditions for the flame spheroidisation processing of these ceramic and glass-ceramic, porous and dense magnetic microspheres are identified. The magnetic properties of the materials provided for controlled induction heating to a constant level (40 – 45 °C), making these microspheres highly appropriate for localised magnetic hyperthermia applications. Complementary, cytocompatibility investigations confirmed the suitability of porous microspheres for biomedical applications. It is suggested that the flame-spheroidised materials developed opens up new opportunities for the rapid manufacture of innovative synergistic biomaterials, towards magnetic hyperthermia applications. 2023-07-21 Thesis (University of Nottingham only) NonPeerReviewed application/pdf en cc_by https://eprints.nottingham.ac.uk/73616/1/PhD%20Thesis_Jesus%20Molinar%20Diaz_final.pdf Molinar Diaz, Jesus (2023) Novel magnetic micro-structured porous materials for biomedical applications. PhD thesis, University of Nottingham. Magnetic nanoparticle hyperthermia; Microspheres (Pharmacy); Porous materials; Biomedical materials |
| spellingShingle | Magnetic nanoparticle hyperthermia; Microspheres (Pharmacy); Porous materials; Biomedical materials Molinar Diaz, Jesus Novel magnetic micro-structured porous materials for biomedical applications |
| title | Novel magnetic micro-structured porous materials for biomedical applications |
| title_full | Novel magnetic micro-structured porous materials for biomedical applications |
| title_fullStr | Novel magnetic micro-structured porous materials for biomedical applications |
| title_full_unstemmed | Novel magnetic micro-structured porous materials for biomedical applications |
| title_short | Novel magnetic micro-structured porous materials for biomedical applications |
| title_sort | novel magnetic micro-structured porous materials for biomedical applications |
| topic | Magnetic nanoparticle hyperthermia; Microspheres (Pharmacy); Porous materials; Biomedical materials |
| url | https://eprints.nottingham.ac.uk/73616/ |