Engineering a Mastoparan Peptide Concatemer Prodrug From CircRNA for Cancer Therapy

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Engineering a Mastoparan Peptide Concatemer Prodrug From CircRNA for Cancer Therapy

CircRNAs are covalently closed loops of RNA formed as products of RNA backsplicing in mammalian cells. Engineered circRNAs containing a desired coding sequence have been produced using self-splicing introns. Translatable circRNAs require an internal ribosomal entry site or m6A methylation site for t...

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Bibliographic Details
Main Author:	Grewcock, Declan
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2023
Subjects:	CircRNA Breast Cancer Mastoparan cancer therapeutics prodrugs
Online Access:	https://eprints.nottingham.ac.uk/73525/

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