Biochemical and genetic analysis of Lhr, a mysterious helicase/glycosylase conserved across species
Changes to DNA structure frequently inhibit essential processes such as DNA replication. Overcoming replication blockage or collapse requires replication-coupled DNA repair enzymes that catalyse removal of aberrant DNA structures and chemically modified bases. The Lhr family of helicases are found t...
| Main Author: | Buckley, Ryan J. |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2023
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/72474/ |
Similar Items
Genetic and biochemical analysis of the Hel308 Helicase in the Archaeon Haloferax volcanii
by: Lever, Rebecca
Published: (2020)
by: Lever, Rebecca
Published: (2020)
Genetic analysis of the Hel308 helicase in the archaeon Haloferax volcanii
by: Gamble-Milner, Rebecca
Published: (2016)
by: Gamble-Milner, Rebecca
Published: (2016)
Genome architecture and DNA replication in Haloferax volcanii
by: Marriott, Hannah
Published: (2018)
by: Marriott, Hannah
Published: (2018)
Genetic and biochemical analysis of the Archaeal Helicase Hel308
by: Simmons, Emily
Published: (2019)
by: Simmons, Emily
Published: (2019)
Mechanisms of Replication Protein A-dependent R-loop resolution by the human DNA repair helicase, HelQ.
by: Betts, Hannah
Published: (2024)
by: Betts, Hannah
Published: (2024)
DNA binding and unwinding by Hel308 helicase requires dual functions of a winged helix domain
by: Northall, Sarah J., et al.
Published: (2017)
by: Northall, Sarah J., et al.
Published: (2017)
Role of Hel308 helicase in origin-independent DNA replication in two species of Haloferax
by: Harrison, Catherine
Published: (2024)
by: Harrison, Catherine
Published: (2024)
Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile
by: van Eijk, Erika, et al.
Published: (2016)
by: van Eijk, Erika, et al.
Published: (2016)
Primase is required for helicase activity and helicase alters the specificity of primase in the enteropathogen Clostridium difficile
by: van Eijk, Erika, et al.
Published: (2016)
by: van Eijk, Erika, et al.
Published: (2016)
Investigating a human DNA repair helicase that supports CRISPR editing
by: Cubbon, Andrew
Published: (2022)
by: Cubbon, Andrew
Published: (2022)
Exploring RECQ Helicase landscape in breast cancer
by: Arora, Arvind
Published: (2019)
by: Arora, Arvind
Published: (2019)
Replication of damaged DNA
by: Upton, Amy Louise
Published: (2009)
by: Upton, Amy Louise
Published: (2009)
Evaluation of DNA repair biomarkers in epithelial ovarian and breast cancers
by: Shoqafi, Ahmed
Published: (2025)
by: Shoqafi, Ahmed
Published: (2025)
Interactions of the Bacillus subtilis DnaE polymerase with replisomal proteins modulate its activity and fidelity
by: Paschalis, Vasileios, et al.
Published: (2017)
by: Paschalis, Vasileios, et al.
Published: (2017)
Structural and genetic analyses of the RdgC protein in Escherichia coli
by: Yu, Jing
Published: (2009)
by: Yu, Jing
Published: (2009)
Engineering a reagentless biosensor for single-stranded DNA
to measure real-time helicase activity in Bacillus
by: Green, Matthew, et al.
Published: (2014)
by: Green, Matthew, et al.
Published: (2014)
Engineering a reagentless biosensor for single-stranded DNA to measure real-time helicase activity in Bacillus
by: Green, Matthew, et al.
Published: (2014)
by: Green, Matthew, et al.
Published: (2014)
Elevated levels of plasma homocysteine, deficiencies in dietary folic acid and uracil–DNA glycosylase impair learning in a mouse model of vascular cognitive impairment
by: Jadavji, Nafisa M., et al.
Published: (2015)
by: Jadavji, Nafisa M., et al.
Published: (2015)
Molecular biology of the DExD-box helicases DDX49 and DDX52
by: Parkes, Ashley J.
Published: (2024)
by: Parkes, Ashley J.
Published: (2024)
Pre-clinical development of human apurinic/apyrimidinic endonuclease (APE1) inhibitors for cancer therapy
by: Mohammed, Mohammed Zubair Khuder
Published: (2011)
by: Mohammed, Mohammed Zubair Khuder
Published: (2011)
DNA replication origins in Haloferax volcanii
by: Hawkins, Michelle
Published: (2009)
by: Hawkins, Michelle
Published: (2009)
Atypical DNA replication in Haloferax volcanii in the absence of replication origins
by: Smith, Victoria Emily
Published: (2022)
by: Smith, Victoria Emily
Published: (2022)
EXPLORING NOVEL MOLECULAR MECHANISMS OF HELQ IN DNA DAMAGE REPAIR
by: Pan, Jin Ke Michele
Published: (2024)
by: Pan, Jin Ke Michele
Published: (2024)
AFM investigations of critical interactions in the Bacillus primosome and Cryogenic AFM a new tool for structural biology
by: Turner, Ian James
Published: (2006)
by: Turner, Ian James
Published: (2006)
Analysis of catalytic and non-catalytic regions of the human DNA repair helicase HelQ
by: Jenkins, T
Published: (2021)
by: Jenkins, T
Published: (2021)
Successful transfer of plasmid DNA into in vitro cells transfected with an inorganic plasmidMg/Al-LDH nanobiocomposite material as a vector for gene expression
by: Masarudin, Mas Jaffri, et al.
Published: (2009)
by: Masarudin, Mas Jaffri, et al.
Published: (2009)
DNA replication in growth conditions that mimic the natural habitat of Haloferax volcanii
by: McCulloch, Bryn
Published: (2021)
by: McCulloch, Bryn
Published: (2021)
Molecular characterisation of DDX49
by: Kapllanaj, Fiorela
Published: (2024)
by: Kapllanaj, Fiorela
Published: (2024)
DNA damage response and anti-apoptotic proteins expression in NPMc+ mutated cells in acute myeloid leukaemia
by: Qutob, Haitham
Published: (2014)
by: Qutob, Haitham
Published: (2014)
Species identification in chicken based processed food
using species-specific polymerase chain reaction / Nik Monaliza Mohamad Yaman
by: Mohamad Yaman, Nik Monaliza
Published: (2017)
by: Mohamad Yaman, Nik Monaliza
Published: (2017)
Application of Whatman FTA card method in oil palm DNA extraction and PCR analysis / Wan Nurhayati Wan Hanafi and Nur Syahirah Abu Bakar
by: Wan Hanafi, Wan Nurhayati, et al.
Published: (2019)
by: Wan Hanafi, Wan Nurhayati, et al.
Published: (2019)
Alternative DNA Repair During Meiosis in the Budding Yeast S.
cerevisiae
by: Reeves, Ryan Peter
Published: (2025)
by: Reeves, Ryan Peter
Published: (2025)
DNA repair in the archaea – an emerging picture
by: White, Malcolm F., et al.
Published: (2018)
by: White, Malcolm F., et al.
Published: (2018)
The half-life of DNA in bone: measuring decay kinetics in 158 dated fossils
by: Allentoft, M., et al.
Published: (2012)
by: Allentoft, M., et al.
Published: (2012)
Descriptive study on the origin and evolution of beta- defensins copy number variable gene using multigenerational family pedigrees
by: Musa, Nurul Azmah
Published: (2019)
by: Musa, Nurul Azmah
Published: (2019)
Assessment of DNA damage and DNA damage response and repair in dormancy-enriched leukemia cells
by: Aldosari, Sahar
Published: (2017)
by: Aldosari, Sahar
Published: (2017)
RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner
by: Parvathaneni, Swetha, et al.
Published: (2017)
by: Parvathaneni, Swetha, et al.
Published: (2017)
Diversity of DNA replication in the archaea
by: Ausiannikava, Darya, et al.
Published: (2017)
by: Ausiannikava, Darya, et al.
Published: (2017)
Molecular Characterization of Avna Library from the Flesh of Durian (Durio Zibethinus Murr.) Clone D24
by: Ky, Huynh
Published: (2005)
by: Ky, Huynh
Published: (2005)
The Application of DNA Molecular Marker Techniques in Hevea Brasiliensis
by: Atan, Safiah
Published: (2001)
by: Atan, Safiah
Published: (2001)
Similar Items
-
Genetic and biochemical analysis of the Hel308 Helicase in the Archaeon Haloferax volcanii
by: Lever, Rebecca
Published: (2020) -
Genetic analysis of the Hel308 helicase in the archaeon Haloferax volcanii
by: Gamble-Milner, Rebecca
Published: (2016) -
Genome architecture and DNA replication in Haloferax volcanii
by: Marriott, Hannah
Published: (2018) -
Genetic and biochemical analysis of the Archaeal Helicase Hel308
by: Simmons, Emily
Published: (2019) -
Mechanisms of Replication Protein A-dependent R-loop resolution by the human DNA repair helicase, HelQ.
by: Betts, Hannah
Published: (2024)