New approaches to the study of nociception: identification and refinement of approaches for the use of Drosophila melanogaster in the drug discovery pipeline
Nociception is highly conserved between invertebrates and vertebrates. The bulk of basic biomedical research into pain and nociception relies on mammalian model systems with accompanying ethical, financial and time pressures. Thus, studies investigating the peripheral mechanisms of nociception in an...
| Main Author: | Smith, Neave |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2023
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/72451/ |
Similar Items
Evaluation of novel anti-cancer drugs using a D.melanogaster cancer model coupled to AP-MALDI mass spectrometry imaging
by: Wong, Kei Fung Carver / KFC
Published: (2025)
by: Wong, Kei Fung Carver / KFC
Published: (2025)
Proteomic Characterization of Inbreeding-Related Cold Sensitivity in Drosophila melanogaster
by: Vermeulen, C.J., et al.
Published: (2013)
by: Vermeulen, C.J., et al.
Published: (2013)
Investigation of Triose Phosphate Isomerase dysfunction and Redox Stress in a Drosophila Melanogaster model of Neurodegenerative Disease
by: Stone, Aelfwin
Published: (2025)
by: Stone, Aelfwin
Published: (2025)
Drosophila heart cell movement to the midline occurs through both cell autonomous migration and dorsal closure
by: Haack, Timm, et al.
Published: (2014)
by: Haack, Timm, et al.
Published: (2014)
Flies who cannot take the heat: Genome-wide gene expression analysis of temperature-sensitive lethality in an inbred line of Drosophila melanogaster
by: Vermeulen, C.J., et al.
Published: (2014)
by: Vermeulen, C.J., et al.
Published: (2014)
Energy dependent reinforcement learning based on the neuronal mechanisms of the olfactory processing in mushroom body
by: Jiang, Jiamu
Published: (2024)
by: Jiang, Jiamu
Published: (2024)
The effects of cisplatin on developing nociceptive pathways
by: Lloyd, Joseph
Published: (2017)
by: Lloyd, Joseph
Published: (2017)
Evaluation of AChE inhibitors and dual AChE/GSK3-β inhibitor as Alzheimer’s disease treatment
by: Uras, G
Published: (2021)
by: Uras, G
Published: (2021)
The role and function of microRNAs in the nervous system
by: Martin, Clare Alice
Published: (2019)
by: Martin, Clare Alice
Published: (2019)
Alphavirus infection and nociception: differential effects on primary mouse dorsal root ganglia
by: Katz, Benjamin J. G.
Published: (2021)
by: Katz, Benjamin J. G.
Published: (2021)
Electroencephalographic changes associated with non-invasive nociceptive stimulus in minimally anaesthetised dogs
by: Kaka, Ubedullah, et al.
Published: (2016)
by: Kaka, Ubedullah, et al.
Published: (2016)
Endocannabinoid modulation of nociceptive processing
by: Norris, Leonie
Published: (2010)
by: Norris, Leonie
Published: (2010)
Modelling planar cell polarity in Drosophila melanogaster
by: Schamberg, Sabine
Published: (2009)
by: Schamberg, Sabine
Published: (2009)
A quantification of the relationship between neuronal
responses in the rat rostral ventromedial medulla and
noxious stimulation-evoked withdrawal reflexes
by: Devonshire, Ian M., et al.
Published: (2015)
by: Devonshire, Ian M., et al.
Published: (2015)
Biochemical characterisation of dystrophin in sensory dendrite and epithelial cells of drosophila melanogaster
by: Wei, Tee Chee
Published: (2020)
by: Wei, Tee Chee
Published: (2020)
Overexpression Of Mirna-975 Induced Immune Genes And Abnormal Spermatogenesis In Drosophila Melanogaster
by: Manickam, Sharvin
Published: (2024)
by: Manickam, Sharvin
Published: (2024)
Optimization of fruity fly (Drosophila melanogaster) culture media for higher yield of offspring
by: Tee, Sui Yee
Published: (2011)
by: Tee, Sui Yee
Published: (2011)
Refining in-vivo models of pulmonary fibrosis
by: Habgood, Anthony
Published: (2018)
by: Habgood, Anthony
Published: (2018)
Homology modeling analysis of GSTD3 from Drosophila melanogaster / Kauthar Mohd Daud
by: Kauthar, Mohd Daud
Published: (2012)
by: Kauthar, Mohd Daud
Published: (2012)
Effects Of A Lactobacilli Probiotic On Survival And Mobility Of Female Drosophila Melanogaster With Alzheimer’s Disease
by: Lim, Hui Ting
Published: (2020)
by: Lim, Hui Ting
Published: (2020)
Effect Of A Lactobacilli Probiotic On Longevity And Mobility Of Male Drosophila Melanogaster With Alzheimer’s Disease
by: Lim, Chin Peng
Published: (2020)
by: Lim, Chin Peng
Published: (2020)
Effect Of A Lactobacilli Probiotic On
Longevity And Mobility Of Male
Drosophila Melanogaster With
Alzheimer’s Disease
by: Chin Peng, Lim
Published: (2020)
by: Chin Peng, Lim
Published: (2020)
Effects Of A Lactobacilli Probiotic
On Survival And Mobility Of
Female Drosophila Melanogaster
With Alzheimer’s Disease
by: Ting Lim, Hui
Published: (2020)
by: Ting Lim, Hui
Published: (2020)
Transcriptomics Analysis Of Coding Genes And Long Non-Coding Rnas In Ageing In Drosophila Melanogaster
by: Hosseinzadeh Bajgiran, Mohammad Morteza
Published: (2022)
by: Hosseinzadeh Bajgiran, Mohammad Morteza
Published: (2022)
Gainfully employing descending controls in acute and chronic pain management
by: White, Kate, et al.
Published: (2018)
by: White, Kate, et al.
Published: (2018)
Proanthocyanidins supplemented diet alter anti-aging-markers and improved lifespan in Drosophila melanogaster model
by: Jaafaru, Mohammed Sani, et al.
Published: (2024)
by: Jaafaru, Mohammed Sani, et al.
Published: (2024)
Cloning and biochemical characterization of CG16936, a putative glutathione transferase in Drosophila Melanogaster / Tanusya Murali
by: Murali, Tanusya
Published: (2014)
by: Murali, Tanusya
Published: (2014)
An in vivo genetic screen of lung function candidate genes using tissue-specific RNAi in Drosophila melanogaster
by: Szamek, Emma
Published: (2025)
by: Szamek, Emma
Published: (2025)
Developmental alterations in noxious-evoked EEG activity recorded from rat primary somatosensory cortex
by: Devonshire, Ian M., et al.
Published: (2015)
by: Devonshire, Ian M., et al.
Published: (2015)
Developmental alterations in noxious-evoked EEG activity recorded from rat primary somatosensory cortex
by: Devonshire, Ian M., et al.
Published: (2015)
by: Devonshire, Ian M., et al.
Published: (2015)
A novel method for delivering ramped cooling reveals rat behaviours at innocuous and noxious temperatures: a comparative study of human psychophysics and rat behaviour
by: Dunham, James P., et al.
Published: (2015)
by: Dunham, James P., et al.
Published: (2015)
Full hydrodynamic reversibility of the weak dimerization of vancomycin and elucidation of its interaction with VanS monomers at clinical concentration
by: Phillips-Jones, Mary K., et al.
Published: (2017)
by: Phillips-Jones, Mary K., et al.
Published: (2017)
Study on the biochemical function of recombinant delta class drosophila melanogaster glutathione s-transferase 3 (DMGSTD3) / Kithalakshmi Vignesvaran
by: Kithalakshmi, Vignesvaran
Published: (2017)
by: Kithalakshmi, Vignesvaran
Published: (2017)
The investigation of chili peppers extract used as
bioinsecticide to control the fruit flies, drosophila
melanogaster / Mohd Aizuddin Abdul Rashid
by: Abdul Rashid, Mohd Aizuddin
Published: (2017)
by: Abdul Rashid, Mohd Aizuddin
Published: (2017)
Manganese-enhanced magnetic resonance imaging depicts brain activity in models of acute and chronic pain: a new window to study experimental spontaneous pain?
by: Devonshire, Ian M., et al.
Published: (2017)
by: Devonshire, Ian M., et al.
Published: (2017)
High calcium scores in coronary CT angiography: Effects of image post-processing on visualization and measurement of coronary lumen diameter
by: Sun, Zhonghua, et al.
Published: (2014)
by: Sun, Zhonghua, et al.
Published: (2014)
Role of the GPR55 receptor in the modulation of joint afferent mechanosensitivity
by: Paton, Kenneth
Published: (2015)
by: Paton, Kenneth
Published: (2015)
The fourth international Peptide Symposium: Discovery to Drugs: The Peptide Pipeline
by: Benson, Heather, et al.
Published: (2008)
by: Benson, Heather, et al.
Published: (2008)
Development and in vitro bioevaluation of cockle shell-calcium carbonate (Aragonite) nanoparticles for intracellular drug delivery
by: Isa, Tijani
Published: (2015)
by: Isa, Tijani
Published: (2015)
The effect of different concentration of simulated body fluid (SBF) on Commercial Portland cement scaffold / Nur Shakirah Mohd Yusof
by: Mohd Yusof, Nur Shakirah
Published: (2019)
by: Mohd Yusof, Nur Shakirah
Published: (2019)
Similar Items
-
Evaluation of novel anti-cancer drugs using a D.melanogaster cancer model coupled to AP-MALDI mass spectrometry imaging
by: Wong, Kei Fung Carver / KFC
Published: (2025) -
Proteomic Characterization of Inbreeding-Related Cold Sensitivity in Drosophila melanogaster
by: Vermeulen, C.J., et al.
Published: (2013) -
Investigation of Triose Phosphate Isomerase dysfunction and Redox Stress in a Drosophila Melanogaster model of Neurodegenerative Disease
by: Stone, Aelfwin
Published: (2025) -
Drosophila heart cell movement to the midline occurs through both cell autonomous migration and dorsal closure
by: Haack, Timm, et al.
Published: (2014) -
Flies who cannot take the heat: Genome-wide gene expression analysis of temperature-sensitive lethality in an inbred line of Drosophila melanogaster
by: Vermeulen, C.J., et al.
Published: (2014)