Origin-independent replication in Haloferax volcanii: RadA localisation, R-loops, and genomic rearrangements

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Origin-independent replication in Haloferax volcanii: RadA localisation, R-loops, and genomic rearrangements

DNA replication typically initiates at origins, DNA sequences at which replication initiator proteins bind and instigate formation of the DNA replication machinery. It was thought that origins of replication are essential across all domains of life. However, the halophilic archaeon Haloferax volcani...

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Bibliographic Details
Main Author:	Hodson, Katie
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2023
Subjects:	Chromatin Immunoprecipitation Sequencing; FLAG-tagged RadA; RadA binding; Origin-independent replication; Recombination-dependent replication
Online Access:	https://eprints.nottingham.ac.uk/72357/

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