Nickel-Catalysed Arylative Cyclisations of Alkynones & Molecular Editing of Cyclic Ketones

QR Code

Nickel-Catalysed Arylative Cyclisations of Alkynones & Molecular Editing of Cyclic Ketones

PART I: NICKEL-CATALYSED ANTI-ARYLMETALLATIVE CYCLISATIONS ONTO KETONES A highly enantioselective and regioselective nickel-catalysed domino reaction of the addition of boronic acids across an alkyne, followed by subsequent cyclisation onto a ketone is reported. The reversible E/Z isomerization of...

Full description

Bibliographic Details
Main Author:	Green, Harley
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2023
Subjects:	alkynes ketones alkenes heterocyclic chemistry
Online Access:	https://eprints.nottingham.ac.uk/72269/

Similar Items

Rhodium-catalysed arylative cyclisations of malonate esters by 1,4-rhodium migration
by: O'Brien, Luke
Published: (2019)

Enantioselective Nickel-Catalysed Arylative and Alkenylative Cyclisations onto Electron-Deficient Alkenes via E/Z Isomerisation
by: Gillbard, Simone Marie
Published: (2023)

Nickel-catalysed enantioselective arylative cyclisations
by: Clarke, Christopher
Published: (2019)

Stereoselective nickel-catalysed arylative cyclisation reactions
by: Panchal, Heena
Published: (2019)

Synthesis of pyrroles by nickel-catalysed arylative cyclisations of alkynamides
by: Chung, Chieh-Hsu
Published: (2019)

The development of photoredox-mediated methods for the aminofunctionalisation of alkenes
by: Dhak, Mandeep Singh
Published: (2023)

Regioselective control of the nickel-mediated coupling of acetylene and carbon dioxide - A DFT study
by: Graham, D., et al.
Published: (2008)

Nickel-catalysed synthesis of multisubstituted pyrroles by anti-carbometallative cyclisations
by: Gillbard, Simone Marie
Published: (2019)

Quantum rotor tunnelling in methyl ethyl ketone and acetophenone studied using field-cycling NMR techniques
by: Abu-Khumra, Sabah
Published: (2013)

Molecular Editing of Indoles via Formal N-Atom Insertion and C–S Cross-Coupling in Micellar Solution
by: Valentine, Gemma
Published: (2023)

Studies towards enantioselective metal-catalysed nucleophilic allylations using allenes
by: Di Sanza, Riccardo
Published: (2020)

Single-Carbon Atom Insertion into Aromatic Heterocycles
by: Joynson, Ben
Published: (2023)

Techno-economic and environmental assessment of CO2 utilisation processes for the production of dimethyl ether and olefins
by: Ahmed, Mohamed
Published: (2023)

Solubility behavior of pure components (camphene and caryophyllene oxide) at subcritical and supercritical conditions of carbon dioxide
by: Yeoh, Hooi Sim
Published: (2014)

N-Heterocyclic carbenes as π*-acceptors in luminescent Re(I) triscarbonyl complexes
by: Casson, L., et al.
Published: (2011)

Synthesis, Characterization and Elucidation of the Structure–Activity Relationship of Heteroatom Donor Ligands and Their Complexes Derived From Substituted Dithiocarbazate Derivatives
by: How, Fiona Ni Foong
Published: (2008)

The Cyclisation of l-Aryl-2-Benzamidoalkan-l-Ols to 4,5-DihydroOxazoles or Isoquinolines
by: Md. Sharif, Atan, et al.
Published: (1990)

Synthesis and Characterisation of Mono- and Bidentate Alkoxybenzimidazolin-2-ylidene Palladium Complexes: Interesting Solution Behaviour and Application in Catalysis
by: Simpson, P., et al.
Published: (2011)

Synthetic routes towards pyrimido[1,2-a][1,3,5]triazines (Review)
by: Dolzhenko, Anton
Published: (2011)

Voltammetric studies of lead (ll), cadmium(ll), copper(ll) and chromium(lll) ions in the presence of selected n-heterocyclic compound
by: Rahman, Nurul Hudah
Published: (2011)

Synthesis, characterization and biological activity of new symmetrical 1,3-benzoxazine compounds
by: Hassan, Chiya Othman
Published: (2017)

Dietary Exposure Among Adults in Selangor, Malaysia, to Heterocyclic Amines and Polycyclic Aromatic Hydrocarbons in Cooked Meat and Fish
by: Jahurul, Md. Haque Akanda
Published: (2010)

C–H insertion as a key step to spiro-oxetanes, scaffolds for drug discovery
by: Nicolle, Simon M., et al.
Published: (2017)

Protecting-group-free site-selective reactions in a metal–organic framework reaction vessel
by: Huxley, Michael T., et al.
Published: (2018)

Diastereoselective synthesis of highly substituted, amino- and pyrrolidino-tetrahydrofurans as lead-like molecular scaffolds
by: Moody, Christopher J., et al.
Published: (2018)

Development of a Deoxygenative Ring Contraction Reaction for Nitrogen Heterocycle Synthesis
by: Atkinson, Nick
Published: (2023)

Effect Of Cooking Methods And Conditions On Heterocyclic Amines Content In Satay And Roasted Marinated Chicken
by: Mohd Mukhtar, Mohd Safzan
Published: (2009)

Evaluation of local spices and herbs as marinating ingredients for the reduction of heterocyclic amines in grilled beef
by: Sepahpour, Shabnam
Published: (2017)

Radical Functionalisation of Alkenes
by: Himmel, Leonard
Published: (2023)

Continuous N-alkylation reactions of amino alcohols using γ-Al2O3 and supercritical CO2: unexpected formation of cyclic ureas and urethanes by reaction with CO2
by: Streng, Emelia S., et al.
Published: (2017)

Towards biologically active heterocycles from renewable aromatic starting materials
by: Anderson, Edward
Published: (2019)

Selective arylation of phenol protected propygyl bromide via pd-catalysed Suzuki coupling reaction: synthesis, mechanistic studies by DFT calculations and their pharmacological aspects
by: Farooq, Hira, et al.
Published: (2018)

Copper(II)-mediated synthesis of indolequinones from bromoquinones and enamines
by: Inman, Martyn, et al.
Published: (2013)

Total synthesis of the post-translationally modified polyazole peptide antibiotic plantazolicin A
by: Wada, Hiroki, et al.
Published: (2015)

Total synthesis of the post-translationally modified polyazole peptide antibiotic goadsporin
by: Dexter, Hannah L., et al.
Published: (2017)

Silver(I) and mercury(II) complexes of meta- and para-xylyl linked bis(imidazol-2-ylidenes)
by: Baker, M., et al.
Published: (2009)

Effect of time and temperature on the simultaneous formation of heterocyclic amines and polycyclic aromatic hydrocarbons using amino acid and sugar model systems
by: Ishak, Ainaatul Asmaa'
Published: (2021)

Bismuth(V) mediated meta-arylation
by: Senior, Aaron James
Published: (2022)

Arylative intramolecular allylation of ketones with 1,3-enynes enabled by catalytic alkenyl-to-allyl 1,4-Rh(I) migration
by: Partridge, Benjamin M., et al.
Published: (2017)

Enantioselective nickel-catalyzed arylative intramolecular allylations of allenyl electrophiles
by: NGUYEN, THI LE NHON
Published: (2020)