Investigating the role of FOSL2 and JUND in the molecular adaptation to hypoxia in colorectal cancer

QR Code

Investigating the role of FOSL2 and JUND in the molecular adaptation to hypoxia in colorectal cancer

Colorectal cancer is a major cause of cancer-related death worldwide, overall ranking third in terms of cancer incidence but second in terms of cancer mortality. Many solid tumours including approximately one third of colorectal tumours feature regions of tumour hypoxia, or low oxygen. Tumour hypoxi...

Full description

Bibliographic Details
Main Author:	Potgieter, Tammy
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2023
Subjects:	Colorectal cancer; Tumour hypoxia; Transcription factors; Hypoxic response
Online Access:	https://eprints.nottingham.ac.uk/72145/

Similar Items

eIF4A2 is a regulator of hypoxic translation and colorectal tumour cell survival
by: Bolland, Hannah
Published: (2020)

Investigating the role of eIF4A2 in the spatial regulation of metabolic adaptation to hypoxia in colorectal cancer
by: Thornton, Luke
Published: (2023)

A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia
by: Foxler, Daniel E., et al.
Published: (2018)

Molecular characterisation of the early metastatic phenotype in colorectal cancer
by: Sculthorpe, Declan
Published: (2024)

Investigating the role of Cut Like Homeobox 1 CUX1 in colorectal cancer progression
by: Rusnita, Dewi
Published: (2024)

Interplay between hypoxia and gastrin in gastrointestinal cancer
by: Royal, E.L.
Published: (2009)

DNA content analysis of colorectal cancer defines a distinct ‘microsatellite and chromosome stable’ group but does not predict response to radiotherapy
by: Fadhil, Wakkas, et al.
Published: (2014)

Accelerated carcinogenesis of colorectal cancer
by: Lam, XiuQian
Published: (2021)

Evaluation of Oxygen-Enhanced MRI for the identification of hypoxia induced treatment resistant tumours in patients with head and neck cancer
by: McCabe, Alastair
Published: (2025)

Role of CD133 in colorectal cancer
by: Ahmed, Tarek Mohamed Abdel Moneim Mohamed Elsaba
Published: (2011)

An investigation of chromosome 20q13 amplification in colorectal cancer
by: Al-masmoum, Hussain
Published: (2016)

The use of molecular and physiological approaches to analyse GROUP VII ETHYLENE RESPONSE FACTORS (ERFVIIs) and the PRT6 N-degron pathway
by: Jones, Dominic
Published: (2020)

Investigating the interactions between tumour cells and the non-tumour cellular community in colorectal cancer
by: Susanti, Susanti
Published: (2021)

The role of factor inhibiting HIF-1 in the cardiovascular responses to hypoxia
by: Platt, Simon
Published: (2022)

Tea, Coffee, and Milk Consumption and Colorectal Cancer Risk
by: Green, C., et al.
Published: (2014)

Human placental renin–angiotensin system in normotensive and pre-eclamptic pregnancies at high altitude and after acute hypoxia–reoxygenation insult
by: Kurlak, L.O., et al.
Published: (2016)

Investigating the role of Cten in metastatic colorectal cancer
by: Thorpe, Hannah
Published: (2016)

Interrogating the genetic profile of sporadic colorectal cancer
by: Fadhil, Wakkas M.
Published: (2019)

Mechanisms and roles of FLYWCH1 in colorectal cancer
by: Onyido, Emenike K.
Published: (2017)

Optimisation of Faecal Immunochemical Test (FIT) for symptomatic colorectal cancer diagnosis
by: Bailey, James Alexander
Published: (2024)

Surgical resection of primary tumour improves aerobic performance in colorectal cancer
by: Williams, John P., et al.
Published: (2014)

Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England
by: Walker, A.J., et al.
Published: (2014)

Human rather than mouse mesenchymal stem cells in 3D co-culture models boost proliferative and migratory characteristics of colorectal cancer cells through paracrine signalling pathways, highlighting species disconnects
by: Lu, M.
Published: (2022)

Systematic review of pre-operative exercise in colorectal cancer patients
by: Boereboom, C., et al.
Published: (2016)

Role and regulation of CTEN in colorectal cancer
by: Alfahed, Abdulaziz/AF
Published: (2020)

Changes in transcription and phospho-signalling in breast tumour hypoxia and hypoxia-reoxygenation
by: Aboalmaaly, Amna
Published: (2024)

Creatinine and myoglobin are poor predictors of anaerobic threshold in colorectal cancer and health
by: Nyasavajjala, Sitaramachandra M., et al.
Published: (2015)

Expression of β-catenin, Ki67 and stroma percentage in colorectal cancer
by: Suanno, Cristina
Published: (2021)

Cost-Effectiveness of an Advance Notification Letter to Increase Colorectal Cancer Screening
by: Cronin, P., et al.
Published: (2013)

Smoking, Alcohol, Diabetes, Obesity, Socioeconomic Status, and the Risk of Colorectal Cancer in a Population-Based Case–Control Study
by: Boyle, T., et al.
Published: (2014)

A Comparison of Continuum and Cell-based Models of Colorectal Cancer
by: Walter, Alexander
Published: (2009)

The role of miRNA regulation in response to hypoxia in gliomas
by: Smith, Louise
Published: (2023)

Studies using the anti-idiotypic monoclonal antibody 105AD7 in patients with advanced and primary colorectal cancer
by: Maxwell-Armstrong, Charles Alan
Published: (1998)

One-third of patients fail to return to work 1 year after surgery for colorectal cancer
by: Bhalla, Ashish, et al.
Published: (2014)

Outcomes in patients undergoing urgent colorectal surgery
by: Teloken, P., et al.
Published: (2014)

UNDERSTANDING THE MECHANISM OF HYPOXIA TOLERANCE IN RICE
by: Oppong, G.K.
Published: (2024)

Investigate tumour heterogeneity and genetic pathways in colorectal cancer
by: Ham Karim, Hersh Abdul
Published: (2017)

Tissue resident CD8 T cells subsets: prognostic significance in colorectal cancer
by: Talhouni, Shahd
Published: (2022)

Dietary patterns and other factors in relation to colorectal cancer risk in Tehran Province, Iran
by: Safari, Akram
Published: (2012)

Histopathological analysis of CD44 and c-Myc in colorectal cancer
by: Littlewood, Stephanie
Published: (2021)