Establishing and Utilising In Vitro Lung Models to Demonstrate Peptide Mediated Non-Viral Delivery

QR Code

Establishing and Utilising In Vitro Lung Models to Demonstrate Peptide Mediated Non-Viral Delivery

Despite their success as gene therapy delivery systems, viral vectors have some unresolved issues; pathogenicity, immunogenicity, and off target effects can be detrimental and sometimes even oncogenic. Commercialised vectors can also still come with a higher price point. An alternative method th...

Full description

Bibliographic Details
Main Author:	Smith, Lauren
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2022
Subjects:	viral vectors non-viral gene therapy delivery peptides
Online Access:	https://eprints.nottingham.ac.uk/71579/

Similar Items

Developing an Oral-Insulin-Delivery System using GET-peptide-mediated transcytosis
by: Rehmani, Sahrish
Published: (2021)

Optimisation of Delivery of the Ataxia Telangiectasia Mutated Transgene to HeLa Cells Using Glycosaminoglycan Enhanced Transduction
by: Siam, Ala'a
Published: (2021)

Developing Mucous Penetrating Particles for Intestinal Gene Delivery using Non-viral GET Peptide System
by: Elnima, Alaa
Published: (2024)

Synthesis and Advanced Characterisation of Nanoparticle Gene Delivery Systems for mRNA therapeutics
by: Khosravi, Rahman
Published: (2025)

Isolation and characterization of viral nervous necrosis virus on newly established marine fish cell line and its pathogenicity in non-marine host
by: Hasoon, Mauida F.
Published: (2011)

Applications of phage peptide libraries for epitope discovery and identification of novel anti-virals
by: Hakami, Abdulrahim R.
Published: (2017)

What triggers sharing in viral marketing? The role of emotion and social feature
by: Li, Boying, et al.
Published: (2015)

Seroprevalence of BVD molecular detection of the virus in cattle and buffaloes and its risk factors in selected farms in Selangor and Sabah, Malaysia
by: Khalid, Nurulhidayah
Published: (2021)

Development of surface plasmon resonance based assay for simultaneous detection of Hepatitis C and B viral infections
by: Akhavanrezaei, Morvarid
Published: (2015)

Hyperbranched polymers as non-viral vectors for gene delivery
by: Alazzo, Ali
Published: (2018)

Identification, prevalence and impacts of viral diseases of UK winter wheat
by: Flint, Laura J.
Published: (2014)

Optimization for detecting the efficiency of viral-vectored gene delivery via intratumoural route in murine model
by: Mustafa, Nor Hidayah
Published: (2015)

Exploiting Multicomponent Polymerisations for Non-Viral Gene Delivery
by: O'Shaughnessy, Lewis
Published: (2025)

Investigation and characterisation of viral and host factors that impact intraspecies EBOV infectivity using a viral pseudotyping assay
by: Dey, Jayasree
Published: (2023)

Bluetongue virus spread in Europe is a consequence of climatic, landscape and vertebrate host factors as revealed by phylogeographic inference
by: Jacquot, Maude, et al.
Published: (2017)

Intraperitoneal delivery of nanoparticles for cancer gene therapy
by: Hallaj-Nezhadi, Somayeh, et al.
Published: (2013)

Assessing the risk of wild rodents as a potential source of emerging virus infections
by: Chappell, Joseph Graham
Published: (2020)

Production Of The Nucleocapsid Protein Of A Swine Nipah Virus Isolate In Escherichia Coli
by: Ong, Swee Tin
Published: (2002)

Mapping of the Functional Domains of the Newcastle Disease Virus Phosphoprotein (P).
by: Jahanshiri, Fatemeh
Published: (2006)

Exploring the diversity and ecology of bacteriophages in the dairy farm environment
by: Cook, Ryan
Published: (2023)

Therapeutic intracellular delivery using magnetic fields, nanoparticle technology and enhanced cell penetrating peptides
by: Blokpoel Ferreras, Lia Andrea
Published: (2019)

Azithromycin reduces airway inflammation induced by human rhinovirus in lung allograft recipients
by: Ling, K.M., et al.
Published: (2019)

The cost of treatment failure: resource use and costs incurred by hepatitis C virus genotype 1-infected patients who do or do not achieve sustained virological response to therapy
by: Backx, M., et al.
Published: (2014)

Word-of-Mouth Marketing in the Music Industry: Are Record Labels Communicating Effectively With Their Target Market?
by: Hoak, Katherine
Published: (2006)

PEGylated enhanced cell penetrating peptide nanoparticles for lung gene therapy
by: Osman, Gizem, et al.
Published: (2018)

Plant-based vaccines for prevention of poultry viral diseases: Newcastle disease
by: Nurzijah, Ika
Published: (2025)

Hypothalamic over-expression of VGF in the Siberian hamster increases energy expenditure and reduces body weight gain
by: Lewis, Jo E., et al.
Published: (2017)

Evaluation of cell-penetrating peptides as tools to improve nose-brain delivery of insulin
by: Brown, Alexander
Published: (2024)

MODIFIED CELL PENETRATING PEPTIDES FOR EFFICIENT POLYMER NANO/MICROPARTICLE DELIVERY FOR BONE DIFFERENTIATION APPLICATIONS
by: Jalal, Aveen
Published: (2020)

A cluster-randomised controlled trial to test the efficacy of facemasks in preventing respiratory viral infection among Hajj pilgrims
by: Wang, Mandy, et al.
Published: (2014)

Evidence for an ancient aquatic origin of the RNA viral order Articulavirales
by: Petrone, M.E., et al.
Published: (2023)

Hepatitis B status in migrants and refugees: increasing health burden in Western Australia
by: Subramaniam, K., et al.
Published: (2011)

The scenario of norovirus contamination in food and food handlers
by: Tuan Zainazor, C., et al.
Published: (2010)

In vitro isolation and molecular identification of reptarenavirus in Malaysia
by: Abba, Yusuf, et al.
Published: (2016)

Induction of autophagy by non-structural protein 6 in important animal and human coronaviruses
by: Daubrah-Scott, Tyler-Josh
Published: (2025)

Functionalising and Preserving Blood Platelets for Biologically Targeted Gene Therapies
by: Al athram, Nairouz
Published: (2025)

Photocatalytic Tryptophan Alkylation for Chemoselective Peptide Modification
by: Lee, Joanna
Published: (2024)

Finding influential ebay buyers for viral marketing - a conceptual model of BuyerRank
by: Lam, Hon, et al.
Published: (2009)

The biodiversity and epidemiology of potato virus Y (PVY) in Scotland
by: Davie, Kim
Published: (2014)

Mixed anionic and cationic polyphosphazene complexes for effective gene delivery to glioblastoma in vitro and in vivo
by: Hsu, Wei-Hsin
Published: (2018)