Connecting MicroRNA and autophagy disturbances in Amyotrophic Lateral Sclerosis (ALS)
Growing evidence implicates miRNA dysregulation as a hallmark of Amyotrophic Lateral Sclerosis (ALS) and there has been increasing interest in their potential as biomarkers of disease. However, no miRNA biomarker signature is currently clinically available. In Chapter 3, we perform a systematic lite...
| Main Author: | Foggin, Sophie |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2022
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/71220/ |
Similar Items
Magnetic resonance microimaging of the spinal cord in the SOD1 mouse model of amyotrophic lateral sclerosis detects motor nerve root degeneration
by: Cowin, G., et al.
Published: (2011)
by: Cowin, G., et al.
Published: (2011)
MicroRNA Regulation in the Inflammatory Response
by: Martin, Athena
Published: (2023)
by: Martin, Athena
Published: (2023)
microRNA network analysis identifies miR-29 cluster as key regulator of LAMA2 in ependymoma
by: Lourdusamy, Anbarasu, et al.
Published: (2015)
by: Lourdusamy, Anbarasu, et al.
Published: (2015)
MicroRNA analysis of the invasive margin of glioblastoma reveals drugable therapeutic targets in lipid metabolism pathways
by: Alfardus, Huda
Published: (2020)
by: Alfardus, Huda
Published: (2020)
Microrna expression and assessment of potential role of miR-181a in head and neck cancer
by: Ab Mutalib, Nurul Syakima
Published: (2012)
by: Ab Mutalib, Nurul Syakima
Published: (2012)
Circulating microRNAs for the prediction of metastasis in breast cancer patients diagnosed with early stage disease
by: Inns, Joseph, et al.
Published: (2015)
by: Inns, Joseph, et al.
Published: (2015)
Epidrug mediated re-expression of miRNA targeting the HMGA transcripts in pituitary cells
by: Kitchen, Mark O., et al.
Published: (2015)
by: Kitchen, Mark O., et al.
Published: (2015)
The role and function of microRNAs in the nervous system
by: Martin, Clare Alice
Published: (2019)
by: Martin, Clare Alice
Published: (2019)
The effects of gonadal tissue/gamete cryopreservation on microRNAs
by: Islam, Nadia
Published: (2020)
by: Islam, Nadia
Published: (2020)
Microrna profiling in type 2 diabetic kidney disease patients, clinical association and prediction of putative targets by bioinformatics
by: Zahari Sham, Siti Yazmin
Published: (2021)
by: Zahari Sham, Siti Yazmin
Published: (2021)
Analysis of V-Ki-Ras2 Kirsten rat sarcoma viral oncogene (Kras) and differential expressed miRNA in various stages of colorectal cancer
by: Lye, Kwan Liang
Published: (2013)
by: Lye, Kwan Liang
Published: (2013)
Effects of microrna-29A-3P and microrna-96-5P on cell invasion and migration in colon cancer cell lines
by: He, Peiyuan
Published: (2015)
by: He, Peiyuan
Published: (2015)
Profiling of gene and exosomal microRNA as therapy targets and biomarkers of cisplatin resistance in triple negative breast cancer stem cell-like subpopulation
by: Koh, May Zie
Published: (2021)
by: Koh, May Zie
Published: (2021)
Mechanisms and roles of FLYWCH1 in colorectal cancer
by: Onyido, Emenike K.
Published: (2017)
by: Onyido, Emenike K.
Published: (2017)
Impact of voluntary exercise and housing conditions on hippocampal glucocorticoid receptor, miR-124 and anxiety
by: Pan-Vazquez, Alejandro, et al.
Published: (2015)
by: Pan-Vazquez, Alejandro, et al.
Published: (2015)
Modelling changes in excitability of the peripheral nervous system using compartmentalised microfluidic culture
by: Rockliffe, Alice
Published: (2021)
by: Rockliffe, Alice
Published: (2021)
Transcriptomic analysis in pediatric spinal ependymoma reveals distinct molecular signatures
by: Lourdusamy, Anbarasu, et al.
Published: (2017)
by: Lourdusamy, Anbarasu, et al.
Published: (2017)
The role of microRNAs in the pre-implantation mammalian embryo
by: Makri, K.D.
Published: (2021)
by: Makri, K.D.
Published: (2021)
Spatiotemporal expression and molecular characterisation of miR-344b and miR-344c in developing mouse brain
by: Leong, Angeline Jia Wen
Published: (2015)
by: Leong, Angeline Jia Wen
Published: (2015)
The role of survivin in autophagy
by: Humphry, Nicola
Published: (2018)
by: Humphry, Nicola
Published: (2018)
Amyotrophic lateral sclerosis: improving care with a multidisciplinary approach.
by: Hogden, A., et al.
Published: (2017)
by: Hogden, A., et al.
Published: (2017)
Autophagy, citrullination and cancer
by: Durrant, LG
Published: (2016)
by: Durrant, LG
Published: (2016)
Metabolic stress and cancer: is autophagy the common denominator and a feasible target?
by: Giuliani, C., et al.
Published: (2014)
by: Giuliani, C., et al.
Published: (2014)
Axonal microRNAs in cortical neuronal development and network connectivity
by: Mesquita-Ribeiro, Raquel
Published: (2019)
by: Mesquita-Ribeiro, Raquel
Published: (2019)
Defective recognition of LC3B by mutant SQSTM1/p62 implicates impairment of autophagy as a pathogenic mechanism in ALS-FTLD
by: Goode, Alice, et al.
Published: (2016)
by: Goode, Alice, et al.
Published: (2016)
Investigation into the subcellular localisation and function of miR-122
by: Winlow, Poppy
Published: (2021)
by: Winlow, Poppy
Published: (2021)
Investigating how tenascin-C regulates miR-155 expression
by: Zordan, N
Published: (2021)
by: Zordan, N
Published: (2021)
Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs
by: Dhir, Ashish, et al.
Published: (2015)
by: Dhir, Ashish, et al.
Published: (2015)
Doxorubicin-induced death in tumour cells and cardiomyocytes: is autophagy the key to improving future clinical outcomes?
by: Tacar, O., et al.
Published: (2013)
by: Tacar, O., et al.
Published: (2013)
Initial Soil Springs Stiffness for laterally loaded Piles
by: Bahrami, Amir, et al.
Published: (2012)
by: Bahrami, Amir, et al.
Published: (2012)
Combinatorial application of tocotrienols and chemotherapeutic drugs enhances apoptosis and autophagy in colorectal cancer cells
by: Tham, Shiau Ying
Published: (2020)
by: Tham, Shiau Ying
Published: (2020)
Induction of autophagy is a key component of all-trans-retinoic acid-induced differentiation in leukemia cells and a potential target for pharmacological modulation
by: Orfali, Nina, et al.
Published: (2015)
by: Orfali, Nina, et al.
Published: (2015)
Identifying potential RNA editing sites from RNA-Sequencing data from human brain tissue
by: North, Francesca Louise
Published: (2018)
by: North, Francesca Louise
Published: (2018)
Biophysical studies of ligand selectivity for the hATG8 family of autophagy proteins
by: Butler, Kevin
Published: (2021)
by: Butler, Kevin
Published: (2021)
Design and development of optical biosensors coupling gold nanoparticles or silver nanoclusters with hybridisation chain reaction
by: Ooi, Jessica Sui Ying
Published: (2025)
by: Ooi, Jessica Sui Ying
Published: (2025)
Biphasic effects of autophagy on decompression bubble-induced endothelial injury
by: Wang, M., et al.
Published: (2019)
by: Wang, M., et al.
Published: (2019)
Interleukin-21 gene polymorphisms in Iranian multiple sclerosis subjects
by: Ahmadloo, Salma
Published: (2012)
by: Ahmadloo, Salma
Published: (2012)
Role of NMNAT2 regulation in cortical primary neurons
by: Konstantoulaki, Katerina
Published: (2019)
by: Konstantoulaki, Katerina
Published: (2019)
Influence Of Personal Preferred Creative Problem-Solving Style And Organisational Creativity Factors On Types Of Lateral Thinking
by: Ow, Alex Chee Kin
Published: (2009)
by: Ow, Alex Chee Kin
Published: (2009)
The future of multiple sclerosis treatments
by: Coclitu, Catalina, et al.
Published: (2016)
by: Coclitu, Catalina, et al.
Published: (2016)
Similar Items
-
Magnetic resonance microimaging of the spinal cord in the SOD1 mouse model of amyotrophic lateral sclerosis detects motor nerve root degeneration
by: Cowin, G., et al.
Published: (2011) -
MicroRNA Regulation in the Inflammatory Response
by: Martin, Athena
Published: (2023) -
microRNA network analysis identifies miR-29 cluster as key regulator of LAMA2 in ependymoma
by: Lourdusamy, Anbarasu, et al.
Published: (2015) -
MicroRNA analysis of the invasive margin of glioblastoma reveals drugable therapeutic targets in lipid metabolism pathways
by: Alfardus, Huda
Published: (2020) -
Microrna expression and assessment of potential role of miR-181a in head and neck cancer
by: Ab Mutalib, Nurul Syakima
Published: (2012)