Measuring ligand concentration where it matters: Assessing the “micro pharmacokinetic/pharmacodynamics” of adenosine receptor ligands

The methods used to determine fundamental pharmacological parameters almost exclusively assume that the concentration of drug in the local environment of the target receptor is equal to the concentration of drug that has been added to the system. It has, however, recently been shown that, dependent...

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Bibliographic Details
Main Author: Lochray, Jack
Format: Thesis (University of Nottingham only)
Language:English
Published: 2022
Subjects:
Online Access:https://eprints.nottingham.ac.uk/69169/