Investigating the role of Y-box binding protein 1 in medulloblastoma tumour progression and drug resistance
Introduction: Medulloblastoma relapse represents the most significant unmet clinical challenge in childhood cancer. In spite of this, our understanding of the molecular biology of relapsed medulloblastoma is limited. Evidence is emerging, however, that the biology of medulloblastoma at relapse diffe...
| Main Author: | Taylor, Louisa |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2022
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/69168/ |
Similar Items
Elucidating the molecular mechanism of drug binding and translocation by the multidrug transporter ABCG2
by: Kapoor, Parth
Published: (2020)
by: Kapoor, Parth
Published: (2020)
Investigating the role of tumour-deposited extracellular matrix in medulloblastoma progression
by: Johnson, James E. C.
Published: (2023)
by: Johnson, James E. C.
Published: (2023)
Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein
by: Mittra, Rituparna, et al.
Published: (2017)
by: Mittra, Rituparna, et al.
Published: (2017)
Development of three-dimensional spheroid models for the analysis of medulloblastoma drug response and metastatic dissemination
by: Roper, Sophie Jayne
Published: (2020)
by: Roper, Sophie Jayne
Published: (2020)
Investigating the role of exosomes in medulloblastoma and their involvement in metastasis
by: Jackson, Hannah Kate
Published: (2017)
by: Jackson, Hannah Kate
Published: (2017)
Exploring the role of multidrug exporters and extracellular vesicles in medulloblastoma chemoresistance
by: Wade, Philippa
Published: (2024)
by: Wade, Philippa
Published: (2024)
Assessment of drug-loaded nanoparticles in a 3D in vitro brain tumour model
by: Ivanov, Delyan Pavlov
Published: (2015)
by: Ivanov, Delyan Pavlov
Published: (2015)
An investigation of metastatic markers in models of paediatric medulloblastoma
by: Nasir, Aishah
Published: (2017)
by: Nasir, Aishah
Published: (2017)
Role of 8-Oxoguanine and its repair mechanisms in paediatric medulloblastoma
by: Imani, Katheeja
Published: (2023)
by: Imani, Katheeja
Published: (2023)
Investigating the role of TWIST1 in medulloblastoma metastasis
by: Cardall, Alice
Published: (2021)
by: Cardall, Alice
Published: (2021)
Investigating the role of Rab GTPases in medulloblastoma pathogenesis
by: Entwistle, Susannah J.
Published: (2024)
by: Entwistle, Susannah J.
Published: (2024)
Identifying factors that control medulloblastoma cell migration using a model of brain-CSF dissemination
by: Aldighieri, Macha
Published: (2020)
by: Aldighieri, Macha
Published: (2020)
Analysing the role of medulloblastoma exosomes as biomarkers and their functional contribution to metastasis
by: Jackson, Hannah K.
Published: (2021)
by: Jackson, Hannah K.
Published: (2021)
Development of a magnetic resonance imaging biomarker to improve prognostication in metastatic medulloblastoma
by: Mitoko, Christine Angeline
Published: (2021)
by: Mitoko, Christine Angeline
Published: (2021)
Drug delivery in a tumour cord model: a computational simulation
by: Hubbard, Matthew E., et al.
Published: (2017)
by: Hubbard, Matthew E., et al.
Published: (2017)
Investigating the role of ascorbic acid and its transporters in medulloblastoma
by: Jones, Manon
Published: (2025)
by: Jones, Manon
Published: (2025)
The impact of medulloblastoma-derived extracellular vesicles on the development of primary cortical neurones
by: McCann, Sophie
Published: (2024)
by: McCann, Sophie
Published: (2024)
Highlights of children with Cancer UK’s workshop on drug delivery in paediatric brain tumours
by: Nailor, Audrey, et al.
Published: (2016)
by: Nailor, Audrey, et al.
Published: (2016)
Cellular & molecular mechanisms of drug resistance in cancer cells mutated for FBXW7 tumour suppressor gene
by: Lorenzi, Federica
Published: (2017)
by: Lorenzi, Federica
Published: (2017)
Mathematical and computational models of drug transport in tumours
by: Groh, C.M., et al.
Published: (2014)
by: Groh, C.M., et al.
Published: (2014)
Roles & mechanisms of NANOG-mediated drug resistance in human colorectal cells
by: Shaheen, Sameerah
Published: (2017)
by: Shaheen, Sameerah
Published: (2017)
Antimicrobial resistance of foodborne pathogens in retail pork
by: Apostolou, Dina
Published: (2019)
by: Apostolou, Dina
Published: (2019)
Medulloblastoma and ependymoma cells display levels of 5-carboxylcytosine and elevated TET1 expression
by: Ramsawhook, Ashley, et al.
Published: (2017)
by: Ramsawhook, Ashley, et al.
Published: (2017)
Characterization of multiple drug-resistants pathogens isolated from clinical and environmental samples from nephrology unit of Hospital Serdang
by: Suntharamurthy, Seenu
Published: (2013)
by: Suntharamurthy, Seenu
Published: (2013)
Pharmacological role of efflux transporters: Clinical implications for medication use during breastfeeding
by: Ahmadzai, Hilai, et al.
Published: (2014)
by: Ahmadzai, Hilai, et al.
Published: (2014)
Inhibition of the lysophosphatidylinositol transporter abcc1 reduces prostate cancer cell growth and sensitizes to chemotherapy
by: Emmanouilidi, Aikaterini, et al.
Published: (2020)
by: Emmanouilidi, Aikaterini, et al.
Published: (2020)
Physical and biological characteristics of multi drug resistance (MDR): an integral approach considering pH and drug resistance in cancer
by: Omran, Ziad, et al.
Published: (2017)
by: Omran, Ziad, et al.
Published: (2017)
Antimicrobials and antimicrobial resistance
by: Smith, Frances
Published: (2017)
by: Smith, Frances
Published: (2017)
Antimicrobial activity of Bacillus velezensis strain PD9 secondary metabolite against methicillin resistant Staphylococcus aureus
by: Baharudin, Mohammad Malik Al-Adil
Published: (2021)
by: Baharudin, Mohammad Malik Al-Adil
Published: (2021)
Understanding the contribution of Resistance-Nodulation-Division family efflux pumps to the lifestyle of Pseudomonas aeruginosa
by: Scales, Danielle
Published: (2023)
by: Scales, Danielle
Published: (2023)
Design and characterization of inhibitory peptides against Bleg1_2478, B3 subclass Metallo-β-lactamase
by: Selvaraju, Gayathri
Published: (2021)
by: Selvaraju, Gayathri
Published: (2021)
In vitro activity of fluconazole and voriconazole against
clinical isolates of Candida spp. by E-test method.
by: Jamal, Farida Fatema @ Farida, et al.
Published: (2010)
by: Jamal, Farida Fatema @ Farida, et al.
Published: (2010)
Translating childhood brain tumour research into clinical practice: the experience of molecular classification and diagnostics
by: Ritzmann, Timothy A., et al.
Published: (2018)
by: Ritzmann, Timothy A., et al.
Published: (2018)
Modelling multidrug resistance driven by efflux pump expression in Gram-negative bacteria
by: Youlden, George
Published: (2021)
by: Youlden, George
Published: (2021)
Antibiotic resistance profile, potential drivers and genotype of Escherichia coli, Salmonella sp. and Vibrio sp. isolated from hybrid red tilapia and Asian seabass in the West Coast of Peninsular Malaysia
by: Dewi, Rita Rosmala
Published: (2022)
by: Dewi, Rita Rosmala
Published: (2022)
Anthelmintic Resistance, Validation of FAMACHA and Effects of Management Practices in Selected Goat Farms in Terengganu, Malaysia.
by: Abdul Aziz, Nor Azlina
Published: (2010)
by: Abdul Aziz, Nor Azlina
Published: (2010)
Knowledge, attitudes and practices related to antibiotic use and resistance patterns among outpatients in Eastern Province, Saudi Arabia
by: Alramadhan, Waeel Hussain
Published: (2015)
by: Alramadhan, Waeel Hussain
Published: (2015)
The structural functionalisation of poly(ß-amino esters) for drug delivery to bacterial biofilms
by: Kasza, Karolina Anna
Published: (2024)
by: Kasza, Karolina Anna
Published: (2024)
Profiling of Virulence Factors and Antibiotic Resistance Genes Among Phylogenetic Groups of Extended-Spectrum-Beta-Lactamase Producing Escherichia Coli
by: Yahya Abdullah Al-Hetar, Khadega
Published: (2011)
by: Yahya Abdullah Al-Hetar, Khadega
Published: (2011)
Studies on the biochemistry of the Targeting domain of Lysostaphin
by: Antoniadou, Eleni
Published: (2004)
by: Antoniadou, Eleni
Published: (2004)
Similar Items
-
Elucidating the molecular mechanism of drug binding and translocation by the multidrug transporter ABCG2
by: Kapoor, Parth
Published: (2020) -
Investigating the role of tumour-deposited extracellular matrix in medulloblastoma progression
by: Johnson, James E. C.
Published: (2023) -
Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein
by: Mittra, Rituparna, et al.
Published: (2017) -
Development of three-dimensional spheroid models for the analysis of medulloblastoma drug response and metastatic dissemination
by: Roper, Sophie Jayne
Published: (2020) -
Investigating the role of exosomes in medulloblastoma and their involvement in metastasis
by: Jackson, Hannah Kate
Published: (2017)