The influence of stromal fibroblast on antigen-presenting cell
function and alteration of their biology

QR Code

The influence of stromal fibroblast on antigen-presenting cell function and alteration of their biology

Dendritic cells (DC) and macrophages (Mɸ) are antigen presenting cells (APC) that orchestrate immune activation, immune and tissue homeostasis, and disease pathology. In the case of Mɸ that act in tissue repair and wound healing, it is important that local inflammation is tightly controlled. Diso...

Full description

Bibliographic Details
Main Author:	Mohammad, Salaheddin
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2022
Subjects:	Adaptive immunity; Fibroblasts; CD4+ cells; CD8+ cells; Tumour cells; Antigen presenting cells; Dendritic cells
Online Access:	https://eprints.nottingham.ac.uk/69103/

Similar Items

Intratumoral interleukin-2/agonist CD40 antibody drives CD4+ - independent resolution of treated-turmors and CD4+ -dependent systemic and memory responses
by: Jackaman, Connie, et al.
Published: (2012)

SCIB2, an antibody DNA vaccine encoding NY-ESO-1 epitopes, induces potent antitumor immunity which is further enhanced by checkpoint blockade
by: Xue, Wei, et al.
Published: (2016)

The impact of stroma and ionising radiation on the plasticity of dendritic cells and macrophages
by: Malecka, Anna A.
Published: (2018)

Inflammation and immunosurveillance in breast cancer
by: Mahmoud, Sahar
Published: (2011)

Immune instructive materials for dendritic cell modulation
by: Kämmerling, Lisa
Published: (2021)

Application of a human primary epithelial-fibroblast co-culture system to study fibrosis
by: Richardson, Jaineeta
Published: (2017)

Development of a human induced pluripotent stem cells (hiPSCs)-derived, universal platform, for generation of immunocompetent multi-tissue organoids
by: Azis, Rizal
Published: (2024)

Therapeutic prospects of extracellular vesicles in cancer treatment
by: Chulpanoval, Daria S., et al.
Published: (2018)

Peripheral killer cells do not differentiate between asthma patients with or without fixed airway obstruction
by: Tubby, Carolyn, et al.
Published: (2016)

Modelling lymphangioleiomyomatosis (LAM) using two-dimensional and three-dimensional in vitro co-culture systems
by: Dongre, Arundhati
Published: (2018)

Development of biomimetic platforms to investigate the influence of the extra-cellular environment on immunological responses
by: Donaldson, Amy Rose
Published: (2017)

Modulation of IL-10 production by CD3/CD55 induced Type 1 regulatory (Tr1) T-cells
by: Musarrat, Tajkia
Published: (2019)

Immune modulatory properties of nanoparticles on human dendritic cells
by: Al-Zahri, Reem
Published: (2018)

The novel roles of DNA damage repair proteins ATM and DNA-PK in the regulation of the ER stress response and IL-23 expression in dendritic cells
by: Shah, Sabaria
Published: (2017)

Enhanced dendritic cell immunotherapy to treat glioblastoma
by: Adhikaree, Jason
Published: (2019)

IL-36α induces maturation of Th1-inducing human MDDC and synergises with IFN-γ to induce high surface expression of CD14 and CD11c
by: Higgins, John, et al.
Published: (2015)

Immunocompetent 3D Model of Human Upper Airway for Disease Modeling and In Vitro Drug Evaluation
by: Harrington, Helen, et al.
Published: (2014)

Subset-specific expression of toll-like receptors by bovine afferent lymph dendritic cells
by: Werling, Dirk, et al.
Published: (2017)

Human mesenchymal stromal cells modulate T-cell immune response via transcriptomic regulation
by: Vellasamy, Shalini, et al.
Published: (2016)

The role of indoleamine 2,3-dioxygenase-aryl hydrocarbon receptor pathway in the TLR4-induced tolerogenic phenotype in human DCs
by: Salazar, Fabián, et al.
Published: (2017)

Phenotypic change and induction of cytokeratin expression during in vitro culture of corneal stromal cells
by: Sidney, Laura E., et al.
Published: (2015)

Studying relationship between increased 5-methylcytosine oxidation and expression of cancer stem cell markers in glioblastoma cell lines
by: Wijeyagumar, Vithusha
Published: (2018)

Membranes, molecules and biophysics: enhancing monocyte derived dendritic cell (MDDC) immunogenicity for improved anti-cancer therapy
by: Rauch, Cyril, et al.
Published: (2013)

Discovering novel immune-modulatory monosaccharides using high-throughput screening strategies
by: Alobaid, Meshal
Published: (2020)

Symbiotic and antibiotic interactions between gut commensal microbiota and host immune system
by: Malys, Mantas Kazimieras, et al.
Published: (2015)

Citrullinated α-enolase is an effective target for anti-cancer immunity
by: Cook, Katherine, et al.
Published: (2018)

Multicomponent analysis of the tumour microenvironment reveals low CD8 T cell number, low stromal caveolin-1 and high tenascin-C and their combination as significant prognostic markers in non-small cell lung cancer
by: Onion, David, et al.
Published: (2017)

Impact of p38 mitogen-activated protein kinase inhibition on immunostimulatory properties of human 6-sulfo LacNAc dendritic cells
by: Langosch, Saskia, et al.
Published: (2016)

Solution structure of a novel T-cell adhesion inhibitor derived from the fragment of ICAM-1 receptor: cyclo(1,8)-Cys-Pro-Arg-Gly-Gly-Ser-Val-Cys
by: Tejo, Bimo Ario, et al.
Published: (2009)

Morphological differences between avian influenza viruses grown in chicken and duck cells, a comparative study
by: Al-Mubarak, Firas
Published: (2014)

'Introducing Dendritic Cells as a Novel Immune-Inspired Algorithm for Anomaly Detection'
by: Greensmith, Julie, et al.
Published: (2005)

'Introducing Dendritic Cells as a Novel Immune-Inspired Algorithm for Anomaly Detection'
by: Greensmith, Julie, et al.
Published: (2005)

Development of a topical therapeutic strategy using corneal derived mesenchymal stromal cells for the treatment of ocular surface disorders
by: Beeken, Lydia
Published: (2023)

Development of nanoparticles for targeted delivery of p38 MAPK inhibitor to myeloid dendritic cells
by: You, Jinge
Published: (2024)

Unique characterisation of Langerhans cells in the spleen of the African catfish (Clarias gariepinus)
by: Zaghloul, Doaa M., et al.
Published: (2017)

Part A - PD-1/PD-L1 blockade in cancer immunotherapy/ Part B - Evaluation of PD-1/PD-L1 immune checkpoint inhibitors in a luciferase-reporter cell-based assay
by: Peredo Aguilar, Maria Azucena
Published: (2023)

Role of the Hedgehog pathway in the pancreatic tumour microenvironment
by: Saini, Francesca
Published: (2014)

Roles & mechanisms of NANOG-mediated drug resistance in human colorectal cells
by: Shaheen, Sameerah
Published: (2017)

Establishment of conditional Wnt5a transgenic embryonic stem cell line and its application during neural differentiation process
by: Mohamed Hisham, Nurul Afiqah
Published: (2017)

Glucose uptake mechanism of muscle cells and adipocytes stimulated by Scoparia dulcis linn extract
by: Beh, Joo Ee
Published: (2011)