Design, optimisation, in vitro and in vivo evaluation of promising once-a-day tablet formulations of the novel antihypertensive drug MT-1207

QR Code

Design, optimisation, in vitro and in vivo evaluation of promising once-a-day tablet formulations of the novel antihypertensive drug MT-1207

Hypertension is the most common cardiovascular disease characterised by elevated systolic and diastolic blood pressure. Globally, around 1.28 billion adults have hypertension with only about 21 % having it under control. Prevalence depends on a range of different factors. Currently, there are many d...

Full description

Bibliographic Details
Main Author:	Vrettos, Napoleon Nikolaos
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2022
Subjects:	Hypertension MT-1207 Sustained-release tablets Hydrophilic matrix Gastroretentive Non-effervescent In vitro buoyancy Drug release Pharmacokinetics
Online Access:	https://eprints.nottingham.ac.uk/68979/

Similar Items

Optimisation of once-a-day oral sustained-release formulations for the novel antihypertensive drug MT-1207
by: Wang, Yuhan
Published: (2022)

Inkjet printing of solid oral dosage forms
by: Cader, Hatim K.
Published: (2019)

Desktop 3D printing of controlled release pharmaceutical bilayer tablets
by: Khaled, Shaban, et al.
Published: (2013)

Extrusion based 3D printing as a novel technique for fabrication of oral solid dosage forms
by: Khaled, Shaban
Published: (2016)

Evaluation of Electrospun Nanofibrous Structures for Drug Release Application
by: Haroosh, Hazim Jasim Mohammed, et al.
Published: (2014)

Morphological Structures and Drug Release Effect of Multiple Electrospun Nanofibre Membrane Systems Based on PLA, PCL and PCL/Magnetic Nanoparticle Composites
by: Haroosh, Hazim, et al.
Published: (2022)

Synchrony nutrient capture via intercropping system from plant residues in a rejuvenated oil palm plantation
by: Kusuma, Alan Purba
Published: (2024)

3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles
by: Khaled, Shaban A., et al.
Published: (2015)

Magnetic resonance imaging quantification of fasted state colonic liquid pockets in healthy humans
by: Murray, Kathryn, et al.
Published: (2017)

Compaction, strength and dissolution characteristics of urea 46% N tablets
by: Shamsudin, Intan Soraya
Published: (2014)

Release currents of IP₃ receptor channel clusters and concentration profiles
by: Thul, Ruediger, et al.
Published: (2004)

Southern brown bandicoots can be successfully returned to the wild after physiological experiments.
by: Cooper, Christine
Published: (2011)

Dissolution characteristics of selected fruit tablets with effervescent agents (pdf symbol pada muka surat references)
by: Saifullah, Md.
Published: (2015)

Controlling salt and aroma perception through the inclusion of air fillers
by: Chiu, Natalie, et al.
Published: (2015)

Influence of Slow-Release Fertilisers on Growth of Rubber (Hevea Brasiliensis) Seedlings
by: Tong, Viet Thinh
Published: (1997)

Effects of formaldehyde catchers on emission of formaldehyde and dimensional stability of rubberwood particleboard
by: Lum, Wei Chen
Published: (2014)

Preparation and characterisation of layered metal hydroxides intercalated with ciprofloxacin and ethacrynic acid for slow drug release
by: Abdul Latip, Ahmad Faiz
Published: (2014)

3D inkjet printing of tablets exploiting bespoke complex geometries for controlled and tuneable drug release
by: Kyobula, Mary, et al.
Published: (2017)

How to screen for non-adherence to antihypertensive therapy
by: Gupta, Pankaj, et al.
Published: (2016)

A novel in vitro framework for understanding aroma interactions with the oronasal mucosa
by: Ford, Clive
Published: (2022)

Desktop 3D printing of controlled release pharmaceutical bilayer tablets
by: Khaled, Shaban A., et al.
Published: (2014)

Formulation and evaluation of effervescent josaphine pineapple tablets
by: Mohd Rosdan, Faridatul Ain
Published: (2014)

Differentiation of embryonic stem cells through controlled release of growth factors from microspheres
by: olaye, eghosa omoregie andrew/ E A O
Published: (2009)

Taste-Aroma-Matrix Interactions Determine Flavour Perception
by: Hollowood, Tracey Ann
Published: (2002)

In vivo evaluation of different formulation strategies for sustained release injectables of a poorly soluble HIV protease inhibitor
by: Muees, Joke, et al.
Published: (2015)

Electrospun PLA/PCL/MPs Nanofibrous Hybrid Composite Structures for Sustained Drug Release
by: Haroosh, Hazim, et al.
Published: (2012)

Montara Well Release: Report on necropsies from birds collected in the Timor Sea
by: Gagnon, Marthe Monique, et al.
Published: (2010)

Mencari formulasi pestisid organotimah berpolimer asli yang berkesan dan ekonomik secara lepasan terkawal atau perlahan
by: M. Yamin, Bohari, et al.
Published: (1991)

Integration of an in vitro renal cellular set of tools with systems biology modelling to predict the renal contribution to the pharmacokinetics of a drug
by: Taylor, Patrick
Published: (2020)

Improvement of Drug Release and Compatibility between Hydrophilic Drugs and Hydrophobic Nanofibrous Composites
by: Haroosh, Hazim, et al.
Published: (2021)

Novel functionalized polymers for nanoparticle formulations with anti cancer drugs
by: Puri, Sanyogitta
Published: (2007)

Electrospun nanofibrous composites to control drug release and interaction between hydrophilic drug and hydrophobic blended polymer matrix
by: Haroosh, Hazim, et al.
Published: (2013)

Management of waterborne pathogens in recreational waters
by: McManus, Alexandra, et al.
Published: (2007)

Improving Nanoparticle Drug loading: Matching Polymer to Drug Properties and making of Polymer coated Drug Nanoparticles
by: ANIMASAWUN, R.K
Published: (2020)

Dispersal potential of Scaevola crassifolia (Goodeniaceae) is influenced by intraspecific variation in fruit morphology along a latitudinal environmental gradient
by: Guja, Lydia, et al.
Published: (2014)

Evaluation of a community pharmacy-based intervention for improving patient adherence to antihypertensives: a randomised controlled trial
by: Lau, R., et al.
Published: (2010)

Withdrawal of antihypertensive medication: a systematic review
by: van der Wardt, Veronika, et al.
Published: (2017)

Generation of anti-inflammatory macrophages for implants and regenerative medicine using self-standing release systems with a phenotype-fixing cytokine cocktail formulation
by: Riabov, Vladimir, et al.
Published: (2017)

Biomaterial modification of urinary catheters with antimicrobials to give long-term broadspectrum antibiofilm activity
by: Fisher, Leanne E., et al.
Published: (2015)

Correlating drug release with microstructure of hydrogel-based delivery systems
by: Prasittisart, Pundarik
Published: (2020)