Oral lipid-based drug delivery approaches to improve the intestinal lymphatic transport and systemic bioavailability of a highly lipophilic drug cannabidiol

QR Code

Oral lipid-based drug delivery approaches to improve the intestinal lymphatic transport and systemic bioavailability of a highly lipophilic drug cannabidiol

Lipid-based formulations play a significant role in oral delivery of lipophilic drugs. Previous studies have shown that natural sesame oil promotes the intestinal lymphatic transport and oral bioavailability of highly lipophilic drug cannabidiol (CBD). However, both lymphatic transport and systemic...

Full description

Bibliographic Details
Main Author:	Feng, Wanshan
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2022
Subjects:	Drug delivery Lipid-based Intestinal lymphatic transport
Online Access:	https://eprints.nottingham.ac.uk/68717/

Similar Items

Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system
by: Lee, Jong Bong, et al.
Published: (2018)

Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation
by: Zgair, Atheer, et al.
Published: (2017)

Targeted bio-distribution of drugs to the lymphatic system
by: Jewell, Adelaide
Published: (2022)

Evaluation of lipid liquid crystalline phase particles as drug delivery vectors
by: Xerri, Rachael
Published: (2021)

Delivery of imiquimod to intestinal lymph nodes following oral administration
by: Chen, Haojie
Published: (2025)

Developing Mucous Penetrating Particles for Intestinal Gene Delivery using Non-viral GET Peptide System
by: Elnima, Alaa
Published: (2024)

Contribution of intestinal lymphatic transport to the antiproliferative effect of delta-9-tetrahydrocannabinol
by: Wong, Jonathan Chi Man
Published: (2017)

Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines
by: Zgair, Atheer, et al.
Published: (2016)

The lymphatic absorption of the retinoids
by: Nankervis, Richard
Published: (1992)

The actions of cannabidiol and palmitoylethanolamide on inflammation and permeability of the gut
by: Couch, Daniel
Published: (2018)

Development of lipid nanocapsules for antiangiogenic treatment of glioblastoma and evaluation of their potential for nose-to-brain drug delivery
by: Pourbaghi Masouleh, Milad
Published: (2019)

Mesenteric Lymphatic Targeting of Antiretroviral agents for Improved Treatment of HIV/AIDS
by: Chu, YenJu
Published: (2023)

Establishment of an in vitro culture system, based on small intestinal crypt organoids, for the investigation of putative small intestinal stem cells
by: Gulino, Maria E.
Published: (2016)

Utility Of A Novel Self-emulsifying System For A Lipophilic Drug With Low Oral Bioavailability
by: Choy , Wai Peng
Published: (2006)

Bowel MRI imaging to investigate drug delivery from coated capsules
by: Sulaiman, Sarah
Published: (2023)

Targeting of lamivudine into the HIV reservoir in mesenteric and peripheral lymph nodes
by: Wong, Abigail
Published: (2024)

Gastrointestinal mucoadhesion, absorption and biodistribution of orally administered chitosan-coated amphotericin B nanostructured lipid carriers (NLC) formulation
by: Tan, Janet Sui Ling
Published: (2020)

Development of multifunctional drug delivery systems based on virus-like nanoparticles for cancer targeting drug delivery
by: Biabanikhankahdani, Roya
Published: (2017)

Nucleoside based self-assembling drugs for localized drug delivery
by: Skilling, Kathryn J., et al.
Published: (2018)

Effect Of Food-drug Interaction On Oral Drug Bioavailability
by: Lim , Sheau Chin
Published: (2006)

Rational engineering of Apoferritin-based nanoparticles for drug delivery
by: Crowhurst, Samuel
Published: (2025)

New injectable scaffolds for cell and drug delivery
by: Hamilton, Lloyd George
Published: (2009)

Role of macrophage and associated cytokines in the regulation of breast tumour lymphovascular invasion
by: Ahmad, N.S.
Published: (2016)

An Investigation Of Liposomes For Oral Delivery Of A Poorly Bioavailable Model Drug: Griseofulvin
by: Ong , Sandy Gim Ming
Published: (2011)

Effect Of Inulin On Oral Bioavailability Of Minerals And Drugs
by: Ong, Hwee Ching
Published: (2010)

Drug delivery across length scales
by: Delcassian, Derfogail, et al.
Published: (2018)

Potential and future scope of nanoemulgel formulation for topical delivery of lipophilic drugs
by: Sengupta, Pinaki, et al.
Published: (2017)

Topical and transdermal drug delivery: From simple potions to smart technologies
by: Benson, Heather, et al.
Published: (2019)

Non-covalent polymer and drug complexes as targeted delivery system for pulmonary delivery
by: Li, Huitong
Published: (2021)

The role of bioactive lipids in pain and inflammation
by: Wong, Amy
Published: (2012)

Effects of Liquid Metabolite Combinations from Lactobacillus Plantarums on Intestinal Microflora, Histology and Growth Performance of Piglets
by: Thu, Tran Van
Published: (2011)

Developing a sprayable drug delivery system for the local delivery of nanoparticles in glioblastoma multiforme
by: McCrorie, Phoebe
Published: (2021)

Improving drug delivery to the lungs as a function of excipient choice
by: Olubi, Rebecca
Published: (2024)

Development of an EGFR-targeted Drug Delivery System for Glioblastoma
by: Zhao, Zi-Ruo
Published: (2023)

Drug delivery systems based on iron oxide magnetite-layered double hydroxide nanoparticles for liver anti-cancer drugs
by: Ebadi, Mona
Published: (2021)

Nanocapsules loaded hydrogels for intra-articular and intra-peritoneal drug delivery
by: Surikutchi, Bhanu Teja
Published: (2020)

Drug-loaded hydrogel microneedles for sustainable transdermal delivery of macromolecular proteins
by: Chandran, Rubhan, et al.
Published: (2025)

Synthesis, characterization and cytotoxicity evaluation of carboxylated carbon nanotubes functionalized with silibinin, betulinic acid and levodopa for drug delivery
by: Tan, Julia Meihua
Published: (2015)

Computational modelling of polymer-based drug delivery systems
by: Mackenzie, R.C.
Published: (2015)

Gastric-targeted drug delivery by learning from Helicobacter pylori
by: Paraskevopoulou, Vasiliki
Published: (2019)