Computational investigation on the mechanism of oxygen tolerance in the radical SAM enzyme lysine 2,3-aminomutase

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Computational investigation on the mechanism of oxygen tolerance in the radical SAM enzyme lysine 2,3-aminomutase

The radical S-adenosylmethionine (AdoMet or SAM) enzyme superfamily represents an ensemble of proteins that are able to catalyse biochemical reactions involving organic radical intermediates. These intermediate radicals then undergo a wide range of reactions, many of them difficult to accomplish in...

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Bibliographic Details
Main Author:	Spadoni, Damiano
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2022
Subjects:	MD simulations radical SAM enzymes redox tuning iron-sulfur cluster
Online Access:	https://eprints.nottingham.ac.uk/68373/

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