Virtual and in vitro screening of the Nottingham Managed Chemical Compound Collection vs Mycobacterium bovis and Mycobacterium tuberculosis cell wall biosynthesis enzyme: InhA.

Virtual and in vitro screening of the Nottingham Managed Chemical Compound Collection vs Mycobacterium bovis and Mycobacterium tuberculosis cell wall biosynthesis enzyme: InhA.

Tuberculosis is a worldwide health concern causing 10 illion new cases and 1.4 million deaths annually. Multi-drug resistance is a further issue limiting effective treatment, with the proportion of cases in this category rising each year. InhA is a key enzyme in the Mycobacterium tuberculosis (M...

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Bibliographic Details
Main Author: Lamont, Malcolm
Format: Thesis (University of Nottingham only)
Language:English
Published: 2021
Subjects:
tuberculosis
drug resistance
INHA
inhibin alpha subunit
Online Access:https://eprints.nottingham.ac.uk/66397/

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