Use of SRPK1 inhibitors for the treatment of Diabetic Retinopathy

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Use of SRPK1 inhibitors for the treatment of Diabetic Retinopathy

Microvascular damage results from ischaemia-driven production of pro- angiogenic vascular endothelial growth factor (VEGF). Proximally spliced VEGF is upregulated in the ischemic diabetic retina and has been implicated as the principal driver of the pathological growth and leakage of blood vessels d...

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Bibliographic Details
Main Author:	Malhi, Naseeb
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2021
Subjects:	Diabetic retinopathy; Serine-Arginine Rich protein kinase-1; SRPK1 inhibitors; Vascular permeability
Online Access:	https://eprints.nottingham.ac.uk/65527/

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