Inhibition of the p38 MAPK pathway in human CD1c+ Dendritic Cells enhances their function for cancer immunotherapy

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Inhibition of the p38 MAPK pathway in human CD1c+ Dendritic Cells enhances their function for cancer immunotherapy

The success of immune checkpoint inhibitors (ICI) in treating chemo-radiotherapy resistant tumours like melanoma has ignited renewed interest in cancer immunotherapy. Despite the success of ICI, a substantial proportion of patients do not respond. The resistance mechanisms used by tumours to evade I...

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Bibliographic Details
Main Author:	Kaur, Aanchal Preet
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2021
Subjects:	Dendritic cells; chemotaxis; co-culture; whole blood assay; phenotyping
Online Access:	https://eprints.nottingham.ac.uk/65509/

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