Inhibition of the p38 MAPK pathway in human CD1c+ Dendritic Cells enhances their function for cancer immunotherapy
The success of immune checkpoint inhibitors (ICI) in treating chemo-radiotherapy resistant tumours like melanoma has ignited renewed interest in cancer immunotherapy. Despite the success of ICI, a substantial proportion of patients do not respond. The resistance mechanisms used by tumours to evade I...
| Main Author: | |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2021
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/65509/ |