In vivo/in vitro investigation of alphaxalone PK/PD sex differences in rats and other species

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In vivo/in vitro investigation of alphaxalone PK/PD sex differences in rats and other species

Alphaxalone is an anaesthetic agent from the neurosteroids class and is currently licensed for cats, dogs and rabbits, while it is also being considered for human use. However, it has been reported that alphaxalone has PK/PD sex differences in rats. The cause of this difference is most likely to be...

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Bibliographic Details
Main Author:	Aldurdunji, Mohammed
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2021
Subjects:	Alphaxalone anaesthetics sex differences population pharmacokinetics poppk rat human rabbit dog monkey
Online Access:	https://eprints.nottingham.ac.uk/65488/

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