Optimal cut-Off values of visceral fat area for predicting metabolic syndrome among type 2 diabetes patients in Ningbo, China

Objective: To examine the optimal cut-off values of visceral fat area (VFA) for predicting metabolic syndrome (MetS) among type 2 diabetes (T2D) patients in Ningbo China. Methods: A total of 1017 subjects were selected from T2D patients who accepted standardized management by the National Standardiz...

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Main Authors: Yang, Xi, Lin, Yi, Xu, Guo-dong, Chen, Yan-shu, Zhou, Ye, Sun, Jing, Li, Li
Format: Article
Language:English
Published: Dove Medical Press Ltd 2021
Subjects:
Online Access:https://eprints.nottingham.ac.uk/65375/
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author Yang, Xi
Lin, Yi
Xu, Guo-dong
Chen, Yan-shu
Zhou, Ye
Sun, Jing
Li, Li
author_facet Yang, Xi
Lin, Yi
Xu, Guo-dong
Chen, Yan-shu
Zhou, Ye
Sun, Jing
Li, Li
author_sort Yang, Xi
building Nottingham Research Data Repository
collection Online Access
description Objective: To examine the optimal cut-off values of visceral fat area (VFA) for predicting metabolic syndrome (MetS) among type 2 diabetes (T2D) patients in Ningbo China. Methods: A total of 1017 subjects were selected from T2D patients who accepted standardized management by the National Standardized Metabolic Disease Management Center at Ningbo First Hospital from March 2018 to January 2020. Demography and medical information were collected through questionnaires. Regional adiposity was examined by a visceral fat analyzer using the dual bioelectrical impedance method. Results: Overall, 769 (75.6%) T2D patients were defined to have MetS. Patients with MetS had higher anthropometric values and biomarkers, compared to those without MetS. VFA was significantly correlated with risk factors of MetS. Further logistic regression models showed that VFA was significantly associated with MetS in men (OR=1.02) and in women (OR=1.03) (P<0.001 for both genders) after controlling for related factors. Receiver-operating characteristic curve analysis demonstrated that the optimal cut-off values of VFA were 84.7 cm2 for men and 81.1 cm2 for women to predict MetS in T2D patients. Conclusion: VFA was associated with MetS and could be an independent predictor of MetS in T2D patients. Clinical Trial Registration: Www.ClinicalTrials.gov, number: NCT03811470.
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spelling nottingham-653752021-06-04T03:35:04Z https://eprints.nottingham.ac.uk/65375/ Optimal cut-Off values of visceral fat area for predicting metabolic syndrome among type 2 diabetes patients in Ningbo, China Yang, Xi Lin, Yi Xu, Guo-dong Chen, Yan-shu Zhou, Ye Sun, Jing Li, Li Objective: To examine the optimal cut-off values of visceral fat area (VFA) for predicting metabolic syndrome (MetS) among type 2 diabetes (T2D) patients in Ningbo China. Methods: A total of 1017 subjects were selected from T2D patients who accepted standardized management by the National Standardized Metabolic Disease Management Center at Ningbo First Hospital from March 2018 to January 2020. Demography and medical information were collected through questionnaires. Regional adiposity was examined by a visceral fat analyzer using the dual bioelectrical impedance method. Results: Overall, 769 (75.6%) T2D patients were defined to have MetS. Patients with MetS had higher anthropometric values and biomarkers, compared to those without MetS. VFA was significantly correlated with risk factors of MetS. Further logistic regression models showed that VFA was significantly associated with MetS in men (OR=1.02) and in women (OR=1.03) (P<0.001 for both genders) after controlling for related factors. Receiver-operating characteristic curve analysis demonstrated that the optimal cut-off values of VFA were 84.7 cm2 for men and 81.1 cm2 for women to predict MetS in T2D patients. Conclusion: VFA was associated with MetS and could be an independent predictor of MetS in T2D patients. Clinical Trial Registration: Www.ClinicalTrials.gov, number: NCT03811470. Dove Medical Press Ltd 2021-03-25 Article PeerReviewed application/pdf en cc_by_nc https://eprints.nottingham.ac.uk/65375/1/Yang-2021-Optimal-cut-off-values-of-visceral-.pdf Yang, Xi, Lin, Yi, Xu, Guo-dong, Chen, Yan-shu, Zhou, Ye, Sun, Jing and Li, Li (2021) Optimal cut-Off values of visceral fat area for predicting metabolic syndrome among type 2 diabetes patients in Ningbo, China. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Volume . pp. 1375-1383. ISSN 1178-7007 Abdominal obesity; Metabolic syndrome; Type 2 diabetes; Visceral fat area http://dx.doi.org/10.2147/DMSO.S304164 doi:10.2147/DMSO.S304164 doi:10.2147/DMSO.S304164
spellingShingle Abdominal obesity; Metabolic syndrome; Type 2 diabetes; Visceral fat area
Yang, Xi
Lin, Yi
Xu, Guo-dong
Chen, Yan-shu
Zhou, Ye
Sun, Jing
Li, Li
Optimal cut-Off values of visceral fat area for predicting metabolic syndrome among type 2 diabetes patients in Ningbo, China
title Optimal cut-Off values of visceral fat area for predicting metabolic syndrome among type 2 diabetes patients in Ningbo, China
title_full Optimal cut-Off values of visceral fat area for predicting metabolic syndrome among type 2 diabetes patients in Ningbo, China
title_fullStr Optimal cut-Off values of visceral fat area for predicting metabolic syndrome among type 2 diabetes patients in Ningbo, China
title_full_unstemmed Optimal cut-Off values of visceral fat area for predicting metabolic syndrome among type 2 diabetes patients in Ningbo, China
title_short Optimal cut-Off values of visceral fat area for predicting metabolic syndrome among type 2 diabetes patients in Ningbo, China
title_sort optimal cut-off values of visceral fat area for predicting metabolic syndrome among type 2 diabetes patients in ningbo, china
topic Abdominal obesity; Metabolic syndrome; Type 2 diabetes; Visceral fat area
url https://eprints.nottingham.ac.uk/65375/
https://eprints.nottingham.ac.uk/65375/
https://eprints.nottingham.ac.uk/65375/