Structure-function correlation and biophysical analysis of a novel 3D in vitro leukaemia model

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Structure-function correlation and biophysical analysis of a novel 3D in vitro leukaemia model

The prognosis for relapsed acute myeloid leukaemia (AML) is poor, with available treatments unable to fully eradicate the leukaemic stem cells (LSCs) from which the heterogeneous AML cell types are considered to arise. LSCs evade treatment by hiding within the bone marrow niche, a property current 2...

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Bibliographic Details
Main Author:	James, Jenna
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2021
Subjects:	Model bone marrow niche; Acute myeloid leukaemia; Drug response; Cancer models; Drug discovery
Online Access:	https://eprints.nottingham.ac.uk/65327/

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