An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta
Lung cancer (LC) mortality, as one of the top cancer deaths in China, has been associated with increased levels of exposure to ambient air pollutants. In this study, different lag times on weekly basis were applied to study the association of air pollutants (PM2.5, PM10, and NO2) and LC mortality in...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier B.V.
2021
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| Online Access: | https://eprints.nottingham.ac.uk/65287/ |
| _version_ | 1848800206024343552 |
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| author | Chung, Chee Yap Yang, Jie He, Jun Yang, Xiaogang Hubbard, Richard Ji, Dongsheng |
| author_facet | Chung, Chee Yap Yang, Jie He, Jun Yang, Xiaogang Hubbard, Richard Ji, Dongsheng |
| author_sort | Chung, Chee Yap |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Lung cancer (LC) mortality, as one of the top cancer deaths in China, has been associated with increased levels of exposure to ambient air pollutants. In this study, different lag times on weekly basis were applied to study the association of air pollutants (PM2.5, PM10, and NO2) and LC mortality in Ningbo, and in subpopulations at different age groups and genders. Furthermore, seasonal variations of pollutant concentrations and meteorological variables (temperature, relative humidity, and wind speed) were analysed. A generalised additive model (GAM) using Poisson regression was employed to estimate the effect of single pollutant model on LC mortality in Yangtze River Delta using Ningbo as a case study. It was reported that there were statistically significant relationships between lung cancer mortality and air pollutants. Increases of 6.2% (95% confidence interval [CI]: 0.2% to 12.6%) and 4.3% (95% CI: 0.1% to 8.5%) weekly total LC mortality with a 3-week lag time were linked to each 10 μg/m3 increase of weekly average PM2.5 and PM10 respectively. The association of air pollutants (PM2.5, PM10 and NO2) and LC mortality with a 3-week lag time was also found statistically significant during periods of low temperature (T < 18 °C), low relative humidity (H < 73.7%) and low wind speed (u < 2.8 m/s), respectively. The female population was found to be more susceptible to the exposure to air pollution than the male population. In addition, the population with an age of 50 years or above was shown to be more sensitive to ambient air pollutant. These outcomes indicated that increased risk of lung cancer mortality was evidently linked to exposure to ambient air pollutant on a weekly basis. The impact of weekly variation on the LC mortality and air pollutant levels should be considered in air pollution-related health burden analysis. |
| first_indexed | 2025-11-14T20:47:52Z |
| format | Article |
| id | nottingham-65287 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T20:47:52Z |
| publishDate | 2021 |
| publisher | Elsevier B.V. |
| recordtype | eprints |
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| spelling | nottingham-652872021-05-07T08:46:15Z https://eprints.nottingham.ac.uk/65287/ An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta Chung, Chee Yap Yang, Jie He, Jun Yang, Xiaogang Hubbard, Richard Ji, Dongsheng Lung cancer (LC) mortality, as one of the top cancer deaths in China, has been associated with increased levels of exposure to ambient air pollutants. In this study, different lag times on weekly basis were applied to study the association of air pollutants (PM2.5, PM10, and NO2) and LC mortality in Ningbo, and in subpopulations at different age groups and genders. Furthermore, seasonal variations of pollutant concentrations and meteorological variables (temperature, relative humidity, and wind speed) were analysed. A generalised additive model (GAM) using Poisson regression was employed to estimate the effect of single pollutant model on LC mortality in Yangtze River Delta using Ningbo as a case study. It was reported that there were statistically significant relationships between lung cancer mortality and air pollutants. Increases of 6.2% (95% confidence interval [CI]: 0.2% to 12.6%) and 4.3% (95% CI: 0.1% to 8.5%) weekly total LC mortality with a 3-week lag time were linked to each 10 μg/m3 increase of weekly average PM2.5 and PM10 respectively. The association of air pollutants (PM2.5, PM10 and NO2) and LC mortality with a 3-week lag time was also found statistically significant during periods of low temperature (T < 18 °C), low relative humidity (H < 73.7%) and low wind speed (u < 2.8 m/s), respectively. The female population was found to be more susceptible to the exposure to air pollution than the male population. In addition, the population with an age of 50 years or above was shown to be more sensitive to ambient air pollutant. These outcomes indicated that increased risk of lung cancer mortality was evidently linked to exposure to ambient air pollutant on a weekly basis. The impact of weekly variation on the LC mortality and air pollutant levels should be considered in air pollution-related health burden analysis. Elsevier B.V. 2021-07-20 Article PeerReviewed application/pdf en cc_by https://eprints.nottingham.ac.uk/65287/1/An%20investigation%20into%20the%20impact%20of%20variations%20of%20ambient%20air%20pollution%20and%20meteorological%20factors%20on%20lung%20cancer%20mortality%20in%20Yangtze%20River%20Delta.pdf Chung, Chee Yap, Yang, Jie, He, Jun, Yang, Xiaogang, Hubbard, Richard and Ji, Dongsheng (2021) An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta. Science of The Total Environment, 779 . p. 146427. ISSN 00489697 Ambient air pollution; Lag time; Lung cancer mortality; Meteorological factors; Modelling; Yangtze River Delta http://dx.doi.org/10.1016/j.scitotenv.2021.146427 doi:10.1016/j.scitotenv.2021.146427 doi:10.1016/j.scitotenv.2021.146427 |
| spellingShingle | Ambient air pollution; Lag time; Lung cancer mortality; Meteorological factors; Modelling; Yangtze River Delta Chung, Chee Yap Yang, Jie He, Jun Yang, Xiaogang Hubbard, Richard Ji, Dongsheng An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta |
| title | An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta |
| title_full | An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta |
| title_fullStr | An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta |
| title_full_unstemmed | An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta |
| title_short | An investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in Yangtze River Delta |
| title_sort | investigation into the impact of variations of ambient air pollution and meteorological factors on lung cancer mortality in yangtze river delta |
| topic | Ambient air pollution; Lag time; Lung cancer mortality; Meteorological factors; Modelling; Yangtze River Delta |
| url | https://eprints.nottingham.ac.uk/65287/ https://eprints.nottingham.ac.uk/65287/ https://eprints.nottingham.ac.uk/65287/ |