Apoferritin delivery of imidazotetrazine agents for targeted brain tumour therapy

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Apoferritin delivery of imidazotetrazine agents for targeted brain tumour therapy

Glioblastoma multiforme (GBM) is an aggressive grade IV astrocytoma. The standard of care for GBM includes surgery, radiotherapy and temozolomide (TMZ; DNA alkylating) chemotherapy. Poor TMZ accumulation at the tumour site, resistance and toxicity, limit the success of this treatment. Some modes of...

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Bibliographic Details
Main Author:	Bouzinab, Kaouthar
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2021
Subjects:	Astrocytomas; Glioblastoma multiforme; Drug delivery systems
Online Access:	https://eprints.nottingham.ac.uk/65136/

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