Apoferritin delivery of imidazotetrazine agents for targeted brain tumour therapy
Glioblastoma multiforme (GBM) is an aggressive grade IV astrocytoma. The standard of care for GBM includes surgery, radiotherapy and temozolomide (TMZ; DNA alkylating) chemotherapy. Poor TMZ accumulation at the tumour site, resistance and toxicity, limit the success of this treatment. Some modes of...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2021
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| Online Access: | https://eprints.nottingham.ac.uk/65136/ |