Investigation of diffuse noxious inhibitory controls in the rat monosodium iodoacetate model of osteoarthritis pain

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Investigation of diffuse noxious inhibitory controls in the rat monosodium iodoacetate model of osteoarthritis pain

Osteoarthritis (OA) is the most common form of arthritis, with chronic pain being the most frequent and debilitating consequence. Current analgesics are inadequate in treating OA pain due to poor efficacy or serious side effects. Mechanistic studies in humans suggest dysfunction of descending inhibi...

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Bibliographic Details
Main Author:	Simmonds, Victoria
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2021
Subjects:	DNIC Osteoarthritis Pain Diffuse noxious inhibitory controls CPM Conditioned pain modulation MIA Monosodium iodoacetate Nociceptive withdrawal reflexes NWR
Online Access:	https://eprints.nottingham.ac.uk/64840/

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