Developing a sprayable drug delivery system for
the local delivery of nanoparticles in
glioblastoma multiforme

QR Code

Developing a sprayable drug delivery system for the local delivery of nanoparticles in glioblastoma multiforme

Glioblastoma multiforme (GBM) is a World Health Organisation classified grade 4 tumour with a dismal median survival time of 14 months from diagnosis and a 16% 2-year survival rate. Current treatment consists of debulking surgery followed by concurrent radiotherapy and temozolomide chemotherapy. Rel...

Full description

Bibliographic Details
Main Author:	McCrorie, Phoebe
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2021
Subjects:	Glioblastoma multiforme Drug delivery system Nanoparticles
Online Access:	https://eprints.nottingham.ac.uk/64553/

Similar Items

Apoferritin delivery of imidazotetrazine agents for targeted brain tumour therapy
by: Bouzinab, Kaouthar
Published: (2021)

Development of an EGFR-targeted Drug Delivery System for Glioblastoma
by: Zhao, Zi-Ruo
Published: (2023)

Identifying the metabolic 'Achilles heel' of adult and paediatric glioblastoma multiforme
by: Wood, James
Published: (2019)

Nanotherapeutics as a localised drug delivery system for the treatment of GBM
by: Vasey, Catherine E
Published: (2021)

Molecular responses of U87-glioblastoma multiform cancer stem cells to HSV-G47Δ oncolytic virus in normoxia and hypoxia tumor microenvironments
by: Reza, Vazifehmand Rodposhtei
Published: (2021)

Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against glioblastoma
by: Smith, Stuart J., et al.
Published: (2014)

Surgical delivery of drug releasing poly(lactic-co-glycolic acid)/poly(ethylene glycol) paste with in vivo effects against glioblastoma
by: Smith, Stuart J., et al.
Published: (2014)

Rational engineering of Apoferritin-based nanoparticles for drug delivery
by: Crowhurst, Samuel
Published: (2025)

Encapsulation of metal complex into apoferritin for drug delivery and prodrug activation
by: Cassioli, Maria Letizia
Published: (2023)

Functionalized ionic-liquid templated mesoporous silica nanoparticles for anticancer drug delivery system
by: Zaharudin, Nurul Syahira
Published: (2018)

Development of a drug delivery agent based on ionic liquids templated mesoporous silica nanoparticles
by: Mohamed Isa, Eleen Dayana
Published: (2017)

Development of lipid nanocapsules for antiangiogenic treatment of glioblastoma and evaluation of their potential for nose-to-brain drug delivery
by: Pourbaghi Masouleh, Milad
Published: (2019)

Biomaterial-based local drug delivery to brain tumors
by: Rahman, Ruman
Published: (2014)

Chlorotoxin as a Drug Delivery System to treat Glioblastoma
by: Fawzy, Ahmed Faadil
Published: (2021)

Development of nanoparticles for targeted delivery of p38 MAPK inhibitor to myeloid dendritic cells
by: You, Jinge
Published: (2024)

Formulation of chitosan-based nanoparticles for delivery of proteins and peptides
by: Vellore Janarthanan, Mohanraj
Published: (2003)

The effect of ageing on the blood-brain barrier: The potential of nanoparticle drug delivery systems to target cerebrovascular changes
by: Bates, Jessica
Published: (2025)

Synthesis, morphological structures and material characterization of electrospun PLA: PCL/magnetic nanoparticle composites for drug delivery
by: Haroosh, Hazim, et al.
Published: (2013)

Development of multifunctional drug delivery systems based on virus-like nanoparticles for cancer targeting drug delivery
by: Biabanikhankahdani, Roya
Published: (2017)

Improving Nanoparticle Drug loading: Matching Polymer to Drug Properties and making of Polymer coated Drug Nanoparticles
by: ANIMASAWUN, R.K
Published: (2020)

Mixed anionic and cationic polyphosphazene complexes for effective gene delivery to glioblastoma in vitro and in vivo
by: Hsu, Wei-Hsin
Published: (2018)

Synthesis and in-vitro toxicity evaluation of anticancer drugs-loaded chitosan nanoparticles as therapeutic nanocarriers for the treatment of hepatocellular carcinoma
by: Mohammed, Albalawi Fahad
Published: (2023)

Evaluation of lipid liquid crystalline phase particles as drug delivery vectors
by: Xerri, Rachael
Published: (2021)

The role of calcium activated and voltage gated potassium channel BK, in glioblastoma multiforme membrane potential.
by: Ratnasingham, Mathuscha
Published: (2024)

Development and in vitro bioevaluation of cockle shell-calcium carbonate (Aragonite) nanoparticles for intracellular drug delivery
by: Isa, Tijani
Published: (2015)

Synthesis and Biological Evaluation of Novel Imidazotetrazines
by: Summers, Helen S
Published: (2019)

Synthesis, characterization and cytotoxicity evaluation of carboxylated carbon nanotubes functionalized with silibinin, betulinic acid and levodopa for drug delivery
by: Tan, Julia Meihua
Published: (2015)

Drug delivery systems based on iron oxide magnetite-layered double hydroxide nanoparticles for liver anti-cancer drugs
by: Ebadi, Mona
Published: (2021)

Nucleoside based self-assembling drugs for localized drug delivery
by: Skilling, Kathryn J., et al.
Published: (2018)

Sugar-coated nanoparticles: Investigating lipid-terminated glycopolymers for targeted nanoparticle delivery of nucleic acids
by: Fiedler, Benjamin
Published: (2024)

Vitamin D3-associated lyotropic liquid crystalline nanoparticles for gemcitabine and thymoquinone delivery for treatment of luminal breast cancer with resistant characteristics
by: Loo, Yan Shan
Published: (2023)

Poly(lactic acid)-poly(ethylene glycol) copolymers for use as drug delivery systems
by: Hagan, Susan Anne
Published: (1998)

Development of a targeted drug delivery system for the treatment of hepatitis C virus infection
by: Baloch, Baby Kanwal
Published: (2012)

Drug-loaded hydrogel microneedles for sustainable transdermal delivery of macromolecular proteins
by: Chandran, Rubhan, et al.
Published: (2025)

Correlating drug release with microstructure of hydrogel-based delivery systems
by: Prasittisart, Pundarik
Published: (2020)

Improving drug delivery to the lungs as a function of excipient choice
by: Olubi, Rebecca
Published: (2024)

Gastric-targeted drug delivery by learning from Helicobacter pylori
by: Paraskevopoulou, Vasiliki
Published: (2019)

Development of a chitosan based glucose responsive nanoparticulate insulin delivery system
by: Yaa, Asantewaa
Published: (2014)

Formulation, characterization and cytotoxicity evaluation of orotic acid and magnesium orotate loaded into gum Arabic and chitosan nanoparticles for drug delivery
by: Abdelkader, Hassani
Published: (2020)

Three-dimensional flower-like brushite crystals prepared from high internal phase emulsion for drug delivery application
by: Hong, Ngee Lim, et al.
Published: (2009)