Targeting Lopinavir to the Mesenteric Lymphatic System by Lipophilic Ester Prodrug Approach for Improved Treatment of HIV/AIDS

QR Code

Targeting Lopinavir to the Mesenteric Lymphatic System by Lipophilic Ester Prodrug Approach for Improved Treatment of HIV/AIDS

Human immunodeficiency virus (HIV) is a lifelong disease that can destroy human immune system, thereby leading to life-threatening acquired immune deficiency syndrome (AIDS). Combined antiretroviral therapy (cART) can efficiently suppress HIV replication, but the cessation of cART usually results in...

Full description

Bibliographic Details
Main Author:	Qin, Chaolong
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2021
Subjects:	HIV protease inhibitors lopinavir antiretroviral therapy
Online Access:	https://eprints.nottingham.ac.uk/64304/

Similar Items

Mesenteric Lymphatic Targeting of Antiretroviral agents for Improved Treatment of HIV/AIDS
by: Chu, YenJu
Published: (2023)

Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system
by: Lee, Jong Bong, et al.
Published: (2018)

Association of beta-defensin gene copy number variation with CD4 count and viral load among Malaysian ethnics hiv patients after HAART initiation
by: Achim, Nurfarahin Hanini
Published: (2020)

Targeting of lamivudine into the HIV reservoir in mesenteric and peripheral lymph nodes
by: Wong, Abigail
Published: (2024)

Effectiveness of clinician client-centered counseling on knowledge, attitudes and sexual bahaviors of antiretroviral therapy patients in Yola, Nigeria
by: Martins, Olutayo Folashade
Published: (2015)

Periportal CD4+ Cell Infiltration Increases in HIV/Hepatitis C Virus–Coinfected Patients Commencing ART, Whereas CD8+ Cells Clear From the Liver
by: Gani, R., et al.
Published: (2014)

Contributing factors towards adherence to antiretroviral therapy among people living with HIV at a University Teaching Hospital in Nigeria
by: Eze, Rosemary Ada
Published: (2022)

Molecular cloning, functional assessment and transcriptome characterization of cysteine protease inhibitor and kunitz trypsin inhibitor from turmeric (Curcuma longa L.)
by: Chan, Seow Neng
Published: (2016)

Tuberculosis (TB)-associated immune reconstitution inflammatory syndrome in TB-HIV co-infected patients in Malaysia: prevalence, risk factors, and treatment outcomes
by: Tan, H.Y., et al.
Published: (2014)

Long-term virological outcome in children on antiretroviral therapy in the UK and Ireland
by: Duong, Trinh, et al.
Published: (2014)

Development of protease deficient Meyerozyma guilliermondii strain so for overexpression of thermostable T1 lipase
by: Lorrine, Okojie Eseoghene
Published: (2022)

Molecular expression, characterization and potential applications of a thermostable alkaline protease from Geobacillus thermoglucosidasius SKF4
by: Dan, Allison Suleiman
Published: (2022)

Patients co-infected with hepatitis C virus (HCV) and human immunodeficiency virus recover genotype cross-reactive neutralising antibodies to HCV during antiretroviral therapy
by: Lee, S., et al.
Published: (2014)

Molecular characterisation of the Ubiquitin-specific protease 15 catalytic domain
by: Ward, Stephanie
Published: (2019)

Effects of bortezomib on HIF-1 and HIF-2 transcriptional activities
by: Abd Aziz, Noraini
Published: (2013)

Performance of symptom-based tuberculosis screening among people living with HIV: Not as great as hoped
by: Ahmad Khan, F., et al.
Published: (2014)

Hepatitis C virus quasispecies and pseudotype analysis from acute infection to chronicity in HIV-1 co-infected individuals
by: Ferns, R. Bridget, et al.
Published: (2016)

Project Khanya: a randomized, hybrid effectiveness-implementation trial of a peer-delivered behavioral intervention for ART adherence and substance use in Cape Town, South Africa.
by: Magidson, Jessica F, et al.
Published: (2020)

The Global Spread of AIDS and HIV
by: O'Hara, Phillip
Published: (2007)

Communication and interaction in the context of routine provider initiated HIV testing and counselling for HIV: the case of Kenya
by: Ndirangu, Eunice Wambui
Published: (2016)

Papular pruritic eruption of human immunodeficiency virus infection
by: Chua, Ser Ling
Published: (2015)

Impact of reminder module on adherence and treatment outcomes among HIV-positive patients on antiretroviral theraphy in Hospital Sungai Buloh, Malaysia
by: Abiola, Abdulrahman Surajudeen
Published: (2015)

Factors associated with human immunodeficiency virus stigma (HIV) among health care workers in Hulu Langat, Selangor
by: Che Ishak, Natalia
Published: (2017)

Essays on health and health care utilization in Botswana
by: Mmopelwa, David
Published: (2021)

Cegah HIV kera : Pindah haiwan ke habitat asal.
by: Berita Harian ,
Published: (2011)

Project Khanya: results from a pilot randomized type 1 hybrid effectiveness-implementation trial of a peer-delivered behavioural intervention for ART adherence and substance use in HIV care in South Africa
by: Magidson, J.F., et al.
Published: (2021)

The characteristics of HIV patients who are long-term responders to nevirapine
by: Tenneti, Vijay Seshadri
Published: (2007)

Annexin A2 antibodies but not inhibitors of the annexin A2 heterotetramer impair productive HIV-1 infection of macrophages in vitro
by: Woodham, Andrew W., et al.
Published: (2016)

Assessment of the protein interaction between coagulation factor XII and corn trypsin inhibitor by molecular docking and biochemical validation
by: Hamad, Badraldin K., et al.
Published: (2017)

Copy number variation of c-c chemokine ligand 3-like 1 (CCL3L1), c-c chemokine receptor type 5 (CCR5) and CCR2 polymorphisms on the outcomes of antiretroviral therapy among Malaysian HIV patients
by: Mohamad Isa, Irma Izani
Published: (2020)

AIDS-Orphanhood and Caregiver HIV/AIDS Sickness Status: Effects on Psychological Symptoms in South African Youth
by: Cluver, L., et al.
Published: (2012)

An exploration of factors influencing adherence to highly active antiretroviral therapy (HAART) among people living with HIV/AIDS in Northern Thailand
by: Ruanjahn, G., et al.
Published: (2010)

Effectiveness of a Randomized Controlled Hiv-Risk-Reduction Program Field Trial with Students at Ahmadu Bello University Zaria
by: Abdulmumin, Saad
Published: (2010)

Healthy minds: Psychosocial interventions for school-aged children affected by HIV/AIDS
by: Cluver, L., et al.
Published: (2012)

Effects of HIV/AIDS educational intervention on knowledge, attitude and practices for primary school teachers in Bichi local government Kano, Nigeria
by: Mustapha, Abdu
Published: (2016)

Multifunctional serine protease inhibitor-coated water-soluble gold nanoparticles as a novel targeted approach for the treatment of inflammatory skin diseases
by: Limón, David, et al.
Published: (2018)

Self-assembling antitumour prodrugs for localised drug delivery
by: Citossi, Francesca
Published: (2016)

Positive parenting for positive parents: HIV/AIDS, poverty, caregiver depression, child behavior, and parenting in South Africa
by: Lachman, J., et al.
Published: (2014)

Nutritional status among people living with HIV receiving antiretroviral medication at Hospital Sungai Buloh, Malaysia
by: Hejazi, Nazisa
Published: (2009)

Validation of a brief stigma-by-association scale for use with HIV/AIDS-affected youth in South Africa
by: Boyes, Mark, et al.
Published: (2013)