Coronavirus disease 19 with gastrointestinal symptoms as initial manifestations: a case report

Since the outbreak of coronavirus disease 2019 (COVID-19) in December 2019, an epidemic has spread rapidly worldwide. COVID-19 is caused by the highly infectious severe acute respiratory syndrome coronavirus-2. A 42-year-old woman presented to hospital who was suffering from epigastric discomfort an...

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Main Authors: Wu, Chun-Yang, Yu, Xiao-Pin, Ma, Ada Hoi Yan, Wang, Li-Ping, Yang, Nai-Bin, Li, Guo-Xiang, Shi, Jie-Jun, Qian, Guo-Qing
Format: Article
Language:English
Published: 2020
Subjects:
Online Access:https://eprints.nottingham.ac.uk/64179/
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author Wu, Chun-Yang
Yu, Xiao-Pin
Ma, Ada Hoi Yan
Wang, Li-Ping
Yang, Nai-Bin
Li, Guo-Xiang
Shi, Jie-Jun
Qian, Guo-Qing
author_facet Wu, Chun-Yang
Yu, Xiao-Pin
Ma, Ada Hoi Yan
Wang, Li-Ping
Yang, Nai-Bin
Li, Guo-Xiang
Shi, Jie-Jun
Qian, Guo-Qing
author_sort Wu, Chun-Yang
building Nottingham Research Data Repository
collection Online Access
description Since the outbreak of coronavirus disease 2019 (COVID-19) in December 2019, an epidemic has spread rapidly worldwide. COVID-19 is caused by the highly infectious severe acute respiratory syndrome coronavirus-2. A 42-year-old woman presented to hospital who was suffering from epigastric discomfort and dyspepsia for the past 5 days. Before the onset of symptoms, she was healthy, and had no travel history to Wuhan or contact with laboratory-confirmed COVID-19 cases. An examination showed chronic superficial gastritis with erosion and esophagitis. Enhanced magnetic resonance imaging of the abdomen showed a lesion in the right lower lobe of the lungs. Chest computed tomography showed multiple ground-glass opacity in the lungs. Reverse transcription-polymerase chain reaction was negative for severe acute respiratory syndrome coronavirus-2. There was no improvement after antibiotic treatment. Polymerase chain reaction performed 2 days later was positive and she was diagnosed with COVID-19. After several days of antiviral and symptomatic treatments, her symptoms improved and she was discharged. None of the medical staff were infected. Clinical manifestations of COVID-19 are nonspecific, making differentiating it from other diseases difficult. This case shows the sequence in which symptoms developed in a patient with COVID-19 with gastrointestinal symptoms as initial manifestations.
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spelling nottingham-641792020-12-28T08:27:28Z https://eprints.nottingham.ac.uk/64179/ Coronavirus disease 19 with gastrointestinal symptoms as initial manifestations: a case report Wu, Chun-Yang Yu, Xiao-Pin Ma, Ada Hoi Yan Wang, Li-Ping Yang, Nai-Bin Li, Guo-Xiang Shi, Jie-Jun Qian, Guo-Qing Since the outbreak of coronavirus disease 2019 (COVID-19) in December 2019, an epidemic has spread rapidly worldwide. COVID-19 is caused by the highly infectious severe acute respiratory syndrome coronavirus-2. A 42-year-old woman presented to hospital who was suffering from epigastric discomfort and dyspepsia for the past 5 days. Before the onset of symptoms, she was healthy, and had no travel history to Wuhan or contact with laboratory-confirmed COVID-19 cases. An examination showed chronic superficial gastritis with erosion and esophagitis. Enhanced magnetic resonance imaging of the abdomen showed a lesion in the right lower lobe of the lungs. Chest computed tomography showed multiple ground-glass opacity in the lungs. Reverse transcription-polymerase chain reaction was negative for severe acute respiratory syndrome coronavirus-2. There was no improvement after antibiotic treatment. Polymerase chain reaction performed 2 days later was positive and she was diagnosed with COVID-19. After several days of antiviral and symptomatic treatments, her symptoms improved and she was discharged. None of the medical staff were infected. Clinical manifestations of COVID-19 are nonspecific, making differentiating it from other diseases difficult. This case shows the sequence in which symptoms developed in a patient with COVID-19 with gastrointestinal symptoms as initial manifestations. 2020-09-10 Article PeerReviewed application/pdf en cc_by_nc https://eprints.nottingham.ac.uk/64179/1/1.pdf Wu, Chun-Yang, Yu, Xiao-Pin, Ma, Ada Hoi Yan, Wang, Li-Ping, Yang, Nai-Bin, Li, Guo-Xiang, Shi, Jie-Jun and Qian, Guo-Qing (2020) Coronavirus disease 19 with gastrointestinal symptoms as initial manifestations: a case report. Journal of International Medical Research, 48 (9). 030006052095225. ISSN 0300-0605 COVID-19; severe acute respiratory syndrome coronavirus-2; gastrointestinal symptoms; angiotensin-converting enzyme 2; lungs; dyspepsia; reverse transcriptase-polymerase chain reaction http://dx.doi.org/10.1177/0300060520952256 doi:10.1177/0300060520952256 doi:10.1177/0300060520952256
spellingShingle COVID-19; severe acute respiratory syndrome coronavirus-2; gastrointestinal symptoms; angiotensin-converting enzyme 2; lungs; dyspepsia; reverse transcriptase-polymerase chain reaction
Wu, Chun-Yang
Yu, Xiao-Pin
Ma, Ada Hoi Yan
Wang, Li-Ping
Yang, Nai-Bin
Li, Guo-Xiang
Shi, Jie-Jun
Qian, Guo-Qing
Coronavirus disease 19 with gastrointestinal symptoms as initial manifestations: a case report
title Coronavirus disease 19 with gastrointestinal symptoms as initial manifestations: a case report
title_full Coronavirus disease 19 with gastrointestinal symptoms as initial manifestations: a case report
title_fullStr Coronavirus disease 19 with gastrointestinal symptoms as initial manifestations: a case report
title_full_unstemmed Coronavirus disease 19 with gastrointestinal symptoms as initial manifestations: a case report
title_short Coronavirus disease 19 with gastrointestinal symptoms as initial manifestations: a case report
title_sort coronavirus disease 19 with gastrointestinal symptoms as initial manifestations: a case report
topic COVID-19; severe acute respiratory syndrome coronavirus-2; gastrointestinal symptoms; angiotensin-converting enzyme 2; lungs; dyspepsia; reverse transcriptase-polymerase chain reaction
url https://eprints.nottingham.ac.uk/64179/
https://eprints.nottingham.ac.uk/64179/
https://eprints.nottingham.ac.uk/64179/