Machining-induced thermal damage in cortical bone: necrosis and micro-mechanical integrity
In bone cutting, the tissue is exposed to necrosis due to temperature elevation, which can significantly influence postoperative results in orthopaedic surgeries. This damage is usually revealed through histological analysis to show the necrotic extent; however, this technique does not capture mecha...
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| Format: | Article |
| Language: | English |
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Elsevier Ltd
2021
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| Online Access: | https://eprints.nottingham.ac.uk/63895/ |
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| author | Robles-Linares, Jose A. Axinte, Dragos Liao, Zhirong Gameros, Andres |
| author_facet | Robles-Linares, Jose A. Axinte, Dragos Liao, Zhirong Gameros, Andres |
| author_sort | Robles-Linares, Jose A. |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | In bone cutting, the tissue is exposed to necrosis due to temperature elevation, which can significantly influence postoperative results in orthopaedic surgeries. This damage is usually revealed through histological analysis to show the necrotic extent; however, this technique does not capture mechanical damage, which is essential for a full material integrity assessment. Here, with micro-mechanics, it is demonstrated that machining-induced damage in bone extends beyond the necrotic region. Drilling with different conditions was performed on ex-vivo bovine cortical bone, inducing different damage degrees. Micro-pillar compression tests were performed in the machined sub-surface to identify changes in properties and failure modes caused by drilling. It was revealed that at high cutting temperatures, the bone near the machined surface suffers from lower modulus (−42%), strength (−41%) and brittle behaviour, whereas the bulk bone remains undamaged with pristine properties and ductile behaviour. Histology was also performed to evaluate necrosis and, surprisingly, it was found that the brittle and weaker bone layer is more than three times larger when compared to the necrotic layer, clearly showing that the drilling thermo-mechanical effect could affect not only biologically, but also micro-mechanically. Consequently, these results reveal another kind of bone damage that has so far been neglected. |
| first_indexed | 2025-11-14T20:45:44Z |
| format | Article |
| id | nottingham-63895 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T20:45:44Z |
| publishDate | 2021 |
| publisher | Elsevier Ltd |
| recordtype | eprints |
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| spelling | nottingham-638952020-12-03T06:11:35Z https://eprints.nottingham.ac.uk/63895/ Machining-induced thermal damage in cortical bone: necrosis and micro-mechanical integrity Robles-Linares, Jose A. Axinte, Dragos Liao, Zhirong Gameros, Andres In bone cutting, the tissue is exposed to necrosis due to temperature elevation, which can significantly influence postoperative results in orthopaedic surgeries. This damage is usually revealed through histological analysis to show the necrotic extent; however, this technique does not capture mechanical damage, which is essential for a full material integrity assessment. Here, with micro-mechanics, it is demonstrated that machining-induced damage in bone extends beyond the necrotic region. Drilling with different conditions was performed on ex-vivo bovine cortical bone, inducing different damage degrees. Micro-pillar compression tests were performed in the machined sub-surface to identify changes in properties and failure modes caused by drilling. It was revealed that at high cutting temperatures, the bone near the machined surface suffers from lower modulus (−42%), strength (−41%) and brittle behaviour, whereas the bulk bone remains undamaged with pristine properties and ductile behaviour. Histology was also performed to evaluate necrosis and, surprisingly, it was found that the brittle and weaker bone layer is more than three times larger when compared to the necrotic layer, clearly showing that the drilling thermo-mechanical effect could affect not only biologically, but also micro-mechanically. Consequently, these results reveal another kind of bone damage that has so far been neglected. Elsevier Ltd 2021-01-01 Article PeerReviewed application/pdf en cc_by_nc_nd https://eprints.nottingham.ac.uk/63895/1/Machining-induced%20thermal%20damage%20in%20cortical%20bone%20Necrosis%20and%20micro-mechanical%20integrity.pdf Robles-Linares, Jose A., Axinte, Dragos, Liao, Zhirong and Gameros, Andres (2021) Machining-induced thermal damage in cortical bone: necrosis and micro-mechanical integrity. Materials & Design, 197 . p. 109215. ISSN 0264-1275 Micro-mechanics; Micro-pillar compression; Bone failure mechanism; Histology; Necrosis; Bone cutting http://dx.doi.org/10.1016/j.matdes.2020.109215 doi:10.1016/j.matdes.2020.109215 doi:10.1016/j.matdes.2020.109215 |
| spellingShingle | Micro-mechanics; Micro-pillar compression; Bone failure mechanism; Histology; Necrosis; Bone cutting Robles-Linares, Jose A. Axinte, Dragos Liao, Zhirong Gameros, Andres Machining-induced thermal damage in cortical bone: necrosis and micro-mechanical integrity |
| title | Machining-induced thermal damage in cortical bone: necrosis and micro-mechanical integrity |
| title_full | Machining-induced thermal damage in cortical bone: necrosis and micro-mechanical integrity |
| title_fullStr | Machining-induced thermal damage in cortical bone: necrosis and micro-mechanical integrity |
| title_full_unstemmed | Machining-induced thermal damage in cortical bone: necrosis and micro-mechanical integrity |
| title_short | Machining-induced thermal damage in cortical bone: necrosis and micro-mechanical integrity |
| title_sort | machining-induced thermal damage in cortical bone: necrosis and micro-mechanical integrity |
| topic | Micro-mechanics; Micro-pillar compression; Bone failure mechanism; Histology; Necrosis; Bone cutting |
| url | https://eprints.nottingham.ac.uk/63895/ https://eprints.nottingham.ac.uk/63895/ https://eprints.nottingham.ac.uk/63895/ |