Total Synthesis of jerantinine alkaloids and a biocatalytic synthesis of 2,6 - Disubstituted tetrahydropyrans using an alcohol dehydrogenase
This thesis is comprised of two sections; The first is a semi synthesis of the cytotoxic natural product jerantinine A. Starting from the natural product tabersonine, isolated from Voacanga africana, which contains the 3 stereocenters present in jerantinine alkaloids set in the correct conformation....
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2020
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| Online Access: | https://eprints.nottingham.ac.uk/63797/ |