Methionine-aromatic interactions in ABCG2 influence mitoxantrone efflux

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Methionine-aromatic interactions in ABCG2 influence mitoxantrone efflux

The ATP-Binding Cassette (ABC) transporters are one of many families of membrane transport proteins that utilise the hydrolysis of ATP to provide the energy required to actively transport substrates against a concentration gradient. Some ABC transporters have been implicated in cancer multidrug resi...

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Bibliographic Details
Main Author:	Azmir, Nur Amirah Hannan
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	ATP-binding cassette transporters; Membrane proteins; Multidrug resistance; Mitoxantrone efflux
Online Access:	https://eprints.nottingham.ac.uk/63776/

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