Targeting DNA repair and hypoxia to improve radioresponse in breast cancer

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Targeting DNA repair and hypoxia to improve radioresponse in breast cancer

Radiotherapy is an essential treatment modality in the clinical management of breast cancers, with an established role to reduce the risk of local recurrences. However, the repair of radiotherapy-induced DNA damage by cancer cells and the presence of tumour hypoxia reduces the efficacy of radiothera...

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Bibliographic Details
Main Author:	Aiyappa, Radhika
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	Breast cancer; Radiotherapy; DNA repair; Radiosensitivity; Novel prodrug
Online Access:	https://eprints.nottingham.ac.uk/63731/

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