Recognition of hepaciviruses by ficolins in different mammalian species

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Recognition of hepaciviruses by ficolins in different mammalian species

Ficolins are polymorphic liver-expressed pattern recognition receptors (PRRs) that contribute to the innate surveillance of virus infections, recognising carbohydrates such as N-acetyl glucosamine, which are components of glycoproteins found on the surface of different viruses. While human ficolin-2...

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Bibliographic Details
Main Author:	Adedeji, Yemisi Oluwatomi
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	HCV EqHV/NPHV Ficolins Innate immunity MBL Pseudoparticles Hepacivirus Protein expression Phylogentic tree Sequence analysis Ficolin-2 Non-human primate ficolin Fusion PCR ELISA Western blot Protein purification Pseudotype infectivity assay Pseudotyped based neutralisation assay Ficolin genes HCV model Antiviral therapy
Online Access:	https://eprints.nottingham.ac.uk/63458/

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