Studying colon cancer using intestinal organoid models for anticancer drug and gene functional analysis

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Studying colon cancer using intestinal organoid models for anticancer drug and gene functional analysis

Colorectal tumours demonstrate broad genetic and phenotypic heterogeneity in comparison to their matched normal tissue. To shed light into this diversity in depth, an advanced in-vitro 3D model capable of self-renewal, self-organisation and exhibit organ functionality is required. Self-renewal of th...

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Bibliographic Details
Main Author:	Kashfi, Seyed Mohammad Hossein
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	Colon cancer Organoids Cell culture Noggin Cancer cell lines Rifabutin F-box genes
Online Access:	https://eprints.nottingham.ac.uk/63073/

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