Optimisation of Peptide Linker-based Fluorescent Ligands for the Histamine H1 Receptor

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Optimisation of Peptide Linker-based Fluorescent Ligands for the Histamine H1 Receptor

The histamine H1 receptor (H1R) is a class A G protein-coupled receptor (GPCR) and as recent studies suggested, is involved in mediating cell proliferation and thus cancer progression. High affinity H1R-selective fluorescent ligands with optimum physicochemical properties would serve as a valuable t...

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Bibliographic Details
Main Author:	Kok, Zhi Yuan
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	Histamine H1 receptor fluorescent ligand BODIPY
Online Access:	https://eprints.nottingham.ac.uk/61521/

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