Optimisation of Peptide Linker-based Fluorescent Ligands for the Histamine H1 Receptor
The histamine H1 receptor (H1R) is a class A G protein-coupled receptor (GPCR) and as recent studies suggested, is involved in mediating cell proliferation and thus cancer progression. High affinity H1R-selective fluorescent ligands with optimum physicochemical properties would serve as a valuable t...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
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2020
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| Online Access: | https://eprints.nottingham.ac.uk/61521/ |