Electrospinning and emerging healthcare and medicine possibilities
Electrospinning forms fibers from either an electrically charged polymer solution or polymer melt. Over the past decades, it has become a simple and versatile method for nanofiber production. Hence, it has been explored in many different applications. Commonly used electrospinning assembles fibers f...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
APL Bioengineering
2020
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| Online Access: | https://eprints.nottingham.ac.uk/61190/ |
| _version_ | 1848799848716828672 |
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| author | Liu, Ziqian Ramakrishna, Seeram Liu, Xiaoling |
| author_facet | Liu, Ziqian Ramakrishna, Seeram Liu, Xiaoling |
| author_sort | Liu, Ziqian |
| building | Nottingham Research Data Repository |
| collection | Online Access |
| description | Electrospinning forms fibers from either an electrically charged polymer solution or polymer melt. Over the past decades, it has become a simple and versatile method for nanofiber production. Hence, it has been explored in many different applications. Commonly used electrospinning assembles fibers from polymer solutions in various solvents, known as solution electrospinning, while melt and near-field electrospinning techniques enhance the versatility of electrospinning. Adaption of additive manufacturing strategy to electrospinning permits precise fiber deposition and predefining pattern construction. This manuscript critically presents the potential of electrospun nanofibers in healthcare applications. Research community drew impetus from the similarity of electrospun nanofibers to the morphology and mechanical properties of fibrous extracellular matrices (ECM) of natural human tissues. Electrospun nanofibrous scaffolds act as ECM analogs for specific tissue cells, stem cells, and tumor cells to realize tissue regeneration, stem cell differentiation, and in vitro tumor model construction. The large surface-to-volume ratio of electrospun nanofibers offers a considerable number of bioactive agents binding sites, which makes it a promising candidate for a number of biomedical applications. The applications of electrospinning in regenerative medicine, tissue engineering, controlled drug delivery, biosensors, and cancer diagnosis are elaborated. Electrospun nanofiber incorporations in medical device coating, in vitro 3D cancer model, and filtration membrane are also discussed. |
| first_indexed | 2025-11-14T20:42:11Z |
| format | Article |
| id | nottingham-61190 |
| institution | University of Nottingham Malaysia Campus |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T20:42:11Z |
| publishDate | 2020 |
| publisher | APL Bioengineering |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | nottingham-611902020-07-23T07:36:57Z https://eprints.nottingham.ac.uk/61190/ Electrospinning and emerging healthcare and medicine possibilities Liu, Ziqian Ramakrishna, Seeram Liu, Xiaoling Electrospinning forms fibers from either an electrically charged polymer solution or polymer melt. Over the past decades, it has become a simple and versatile method for nanofiber production. Hence, it has been explored in many different applications. Commonly used electrospinning assembles fibers from polymer solutions in various solvents, known as solution electrospinning, while melt and near-field electrospinning techniques enhance the versatility of electrospinning. Adaption of additive manufacturing strategy to electrospinning permits precise fiber deposition and predefining pattern construction. This manuscript critically presents the potential of electrospun nanofibers in healthcare applications. Research community drew impetus from the similarity of electrospun nanofibers to the morphology and mechanical properties of fibrous extracellular matrices (ECM) of natural human tissues. Electrospun nanofibrous scaffolds act as ECM analogs for specific tissue cells, stem cells, and tumor cells to realize tissue regeneration, stem cell differentiation, and in vitro tumor model construction. The large surface-to-volume ratio of electrospun nanofibers offers a considerable number of bioactive agents binding sites, which makes it a promising candidate for a number of biomedical applications. The applications of electrospinning in regenerative medicine, tissue engineering, controlled drug delivery, biosensors, and cancer diagnosis are elaborated. Electrospun nanofiber incorporations in medical device coating, in vitro 3D cancer model, and filtration membrane are also discussed. APL Bioengineering 2020-07-14 Article PeerReviewed application/pdf en cc_by https://eprints.nottingham.ac.uk/61190/1/Title%20Pages.pdf Liu, Ziqian, Ramakrishna, Seeram and Liu, Xiaoling (2020) Electrospinning and emerging healthcare and medicine possibilities. APL Bioengineering, 4 (3). 030901. ISSN 2473-2877 http://dx.doi.org/10.1063/5.0012309 10.1063/5.0012309 10.1063/5.0012309 10.1063/5.0012309 |
| spellingShingle | Liu, Ziqian Ramakrishna, Seeram Liu, Xiaoling Electrospinning and emerging healthcare and medicine possibilities |
| title | Electrospinning and emerging healthcare and medicine possibilities |
| title_full | Electrospinning and emerging healthcare and medicine possibilities |
| title_fullStr | Electrospinning and emerging healthcare and medicine possibilities |
| title_full_unstemmed | Electrospinning and emerging healthcare and medicine possibilities |
| title_short | Electrospinning and emerging healthcare and medicine possibilities |
| title_sort | electrospinning and emerging healthcare and medicine possibilities |
| url | https://eprints.nottingham.ac.uk/61190/ https://eprints.nottingham.ac.uk/61190/ https://eprints.nottingham.ac.uk/61190/ |