The mitochondrial basis of ageing and neurodegeneration

QR Code

The mitochondrial basis of ageing and neurodegeneration

One of the greatest achievements of the past 150 years is the extraordinary extension of average human lifespan. However, increasing average lifespan is coupled to an insidious rise in age-related cognitive decline and muscle loss. Indeed, progressive age is the number one risk factor for non-commun...

Full description

Bibliographic Details
Main Author:	Ingram, Thomas Liam
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	Mitochondria Ageing Neurodegeneration Comparative biology Parkinson's disease
Online Access:	https://eprints.nottingham.ac.uk/60760/

Similar Items

Does the activity of the proteasome decline during human ageing and in the brains of Parkinson’s disease patients?
by: Wayne, Declan
Published: (2018)

Analysis of mitochondrial haemoglobin in Parkinson's disease brain
by: Shephard, Freya, et al.
Published: (2016)

Mitochondrial proteomic profiling reveals increased carbonic anhydrase II in aging and neurodegeneration
by: Pollard, Amelia, et al.
Published: (2016)

Mouse mitochondrial lipid composition is defined by age in brain and muscle
by: Pollard, Amelia K., et al.
Published: (2017)

METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: an initiative of the Joint Programme for Neurodegenerative Disease Research
by: Dichgans, Martin, et al.
Published: (2016)

Impulse control behaviours in a Malaysian Parkinson’s disease population
by: Md. Rani, Shahrul Azmin, et al.
Published: (2016)

Mitochondrial mistranslation modulated by metabolic stress causes cardiovascular disease and reduced lifespan
by: Richman, T.R., et al.
Published: (2021)

Elevated 5hmC levels characterize DNA of the cerebellum in Parkinson’s disease
by: Stöger, Reinhard, et al.
Published: (2017)

The N-terminus of survivin is a mitochondrial-targeting sequence and Src regulator
by: Dunajova, Lucia, et al.
Published: (2016)

Assessing and treating conversations with partners in Parkinson’s disease: A scoping review of the evidence
by: Thilakaratne, Ramishka, et al.
Published: (2021)

The bacterial secondary metabolite 2,4-diacetylphloroglucinol impairs mitochondrial function and affects calcium homeostasis in Neurospora crassa
by: Troppens, Danielle, et al.
Published: (2013)

Roles of mitochondria in modulating chicken innate immunity following newcastle disease virus infection
by: Mohamad Wali, Haryati Shila
Published: (2019)

Assessing DNA methylation epialleles for human cognitive dysfunction and brain disease
by: Rielly, Nicholas Jude
Published: (2020)

Exercise and Parkinson's: benefits for cognition and quality of life
by: Cruise, K., et al.
Published: (2011)

Limbic grey matter changes in early Parkinson's disease
by: Li, Xingfeng, et al.
Published: (2017)

Mitochondrial uncoupling protein 1 overexpression increases yield in Nicotiana Tabacum under drought stress by improving source and sink metabolism
by: Barreto, Pedro, et al.
Published: (2017)

Therapeutic concentrations of antidepressants inhibit pancreatic beta-cell function via mitochondrial complex inhibition
by: Elmorsy, Ekramy, et al.
Published: (2017)

Effect of simvastatin on vascular tone in porcine coronary artery: potential role of the mitochondria
by: Almukhtar, H., et al.
Published: (2016)

Mitochondrial haemoglobin and ATP synthase – molecular interactions in health and disease
by: Ebanks, Brad
Published: (2023)

On-Demand Dopamine Receptor Activation via Photoresponsive Nanoparticle-Dopamine Conjugates with an Emphasis on Parkinson’s Disease
by: Alghamdi, Hajar
Published: (2024)

Effects of music-based voice intervention protocol on vocal amplitude, pitch range, respiratory rate, and quality of life of people with Parkinson’s Disease
by: Ang, Mei Foong
Published: (2019)

Global DNA methylation profiling of manganese-exposed human neuroblastoma SH-SY5Y cells reveals epigenetic alterations in Parkinson’s disease-associated genes
by: Tarale, Prashant, et al.
Published: (2016)

Would people with Parkinson's disease benefit from palliative care?
by: Hudson, P., et al.
Published: (2006)

Mitochondrial DNA haplogroups and ageing mechanisms in osteoarthritis
by: Valdes, Ana M., et al.
Published: (2017)

Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Alzheimer’s and Parkinson’s diseases
by: Guerreiro, Rita, et al.
Published: (2016)

Evaluation of AChE inhibitors and dual AChE/GSK3-β inhibitor as Alzheimer’s disease treatment
by: Uras, G
Published: (2021)

Fidelity and coordination of mitochondrial protein synthesis in health and disease
by: Rudler, D.L., et al.
Published: (2021)

Personality affects aspects of health-related quality of life in Parkinson’s disease via psychological coping strategies.
by: Whitworth, Stephanie, et al.
Published: (2013)

Delayed administration of dopaminergic drugs is not associated with prolonged length of stay of hospitalized patients with Parkinson's disease
by: Skelly, Rob, et al.
Published: (2017)

Mutation analysis of sporadic early-onset Alzheimer's disease using the NeuroX array
by: Barber, Imelda S., et al.
Published: (2017)

Measuring General Expectations of Advanced Stage Treatment Outcomes in Parkinson's Disease
by: Loftus, Andrea, et al.
Published: (2021)

Understanding the role of mitochondrial haemoglobin - an in silico approach
by: Katyal, Gunjan
Published: (2022)

Axon pathology in mouse models of Huntington's disease
by: Marangoni, Martina
Published: (2014)

Exploring the effects of ageing, cancer, and exercise on skeletal muscle mitochondrial function
by: Smart, Thomas
Published: (2024)

Understanding the impact, accessibility and diversity of Nordic walking in people with Parkinson's Disease
by: McCracken, Sarah Jane
Published: (2024)

Coping processes and health-related quality of life in Parkinson’s disease
by: Bucks, R., et al.
Published: (2011)

Does trajectory matter? A study looking into the relationship of trajectory with target engagement and error accommodation in subthalamic nucleus deep brain stimulation
by: Steel, David Anthony, et al.
Published: (2017)

Performance of drivers with Parkinson's Disease under the effect of cognitive overloading: insinuation for assessment and training
by: Chee, Derserri, et al.
Published: (2013)

Patterns and Predictors of Mental Health Service Utilization in People With Parkinson's Disease
by: Troeung, Lakkhina, et al.
Published: (2014)

ROS in platelet biology: Functional aspects and methodological insights
by: Masselli, E., et al.
Published: (2020)