Comparison of hepatoma cell lines and primary human hepatocytes as models to study the development of hepatic steatosis

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Comparison of hepatoma cell lines and primary human hepatocytes as models to study the development of hepatic steatosis

Non-alcoholic fatty liver disease (NAFLD) is a worldwide health burden. The first stage is the accumulation of fat within hepatocytes (hepatic steatosis). Dietary and genetic factors determine steatosis, with particular emphasis on dietary fat, dietary sugars, and patatin-like phospholipase domain c...

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Bibliographic Details
Main Author:	Huggett, Zoe
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	Hepatic steatosis Non-alcoholic fatty liver disease Lipid accumulation Hepatic lipid metabolism
Online Access:	https://eprints.nottingham.ac.uk/60701/

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