Too little and too much: investigating the role of balanced prefrontal neural activity in behavioural flexibility

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Too little and too much: investigating the role of balanced prefrontal neural activity in behavioural flexibility

A consistent deficit of schizophrenia, among numerous neuropsychiatric disorders, is impaired cognitive flexibility, the prefrontal-dependent ability to overcome pre-existing behavioural strategies to adjust behaviour in line with changing environmental demands. Prefrontal gamma-aminobutyric acid (G...

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Bibliographic Details
Main Author:	Hock, Rebecca M.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	Cognitive flexibility Behavioural flexibility Strategy shifting GABA Disinhibition Operant strategy set-shifting task (operant SST) Attentional set-shifting task (non-automated SST) Medial prefrontal cortex (mPFC)
Online Access:	https://eprints.nottingham.ac.uk/60573/

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