Characterization of the cellular and molecular profiles of CDH1-re-expressed Breast Adenocarcinoma Cells (MDA-MB-231) treated with Zebularine and Trichostatin A followed by Tumour Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)

QR Code

Characterization of the cellular and molecular profiles of CDH1-re-expressed Breast Adenocarcinoma Cells (MDA-MB-231) treated with Zebularine and Trichostatin A followed by Tumour Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)

Breast cancer (BC) is a heterogeneous disease of which its definite cure had yet to be discovered. Tumour Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) is one potential anti-cancer protein with its selective killing on cancerous cells while largely evading the healthy cells. Nonetheless,...

Full description

Bibliographic Details
Main Author:	Wong, Sonia How Ming
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2020
Subjects:	breast cancer Tumour Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) cancer cell anti-cancer protein anti-apoptotic proteins
Online Access:	https://eprints.nottingham.ac.uk/59629/

Similar Items

Evaluation of transcriptional cyclin dependent kinase inhibitors as potential cancer therapeutics
by: Liu, Xiangrui
Published: (2012)

Key cell signaling pathways modulated by zerumbone: Role in the prevention and treatment of cancer
by: Prasannan, R., et al.
Published: (2012)

Synthesis of ganoderic acid analogues to investigate their activity as anti-prostate cancer agents
by: Al-Obaidi, Mohammed
Published: (2019)

Insulin promotes vascular smooth muscle cell proliferation and apoptosis via differential regulation of tumor necrosis factor‐related apoptosis‐inducing ligand
by: Harith, Hanis Hazeera, et al.
Published: (2016)

Development and Encapsulation of Affibody-Apoferritin Biologics for the Targeted Treatment of Breast Cancer
by: Holden, Isobel R
Published: (2025)

Mapping Of Nucleocapsid Protein (Np) Epitopes and Np-Phosphoprotein Interactive Domains of Newcastle Disease Virus with Np Monoclonal Antibodies
by: Ahmad Raus, Raha
Published: (2006)

Anti-inflammatory effects of asiaticoside on tumor necrosis factor-α and interferon-ᵧ Induced raw 264.7 macrophage
by: Zainudin, Nurfarahdilla
Published: (2016)

Examining the importance of survivin phosphorylation at Threonine 5 through its relationship with the kinase, TBK1, and the substrate, c-Src
by: Lishak, Jamie
Published: (2019)

Novel orlistat LDL-like nanoparticles as potential anti-cancer medicines
by: Bebawy, George
Published: (2022)

The inter-relationship between p53, survivin and XIAP in colorectal cancer cells response to apoptotic stimuli
by: Atakpa, Isaac
Published: (2024)

Truncated chicken anemia virus-VP3 as a potential anti tumour vaccine
by: Lim, Shen Ni
Published: (2012)

Biomedical application of OrbiSIMS in cancer: identification of anti-cancer agents and metabolite profiles
by: Lu, Yonghui
Published: (2023)

Zebularine and trichostatin a sensitized human breast adenocarcinoma cells towards tumour necrosis-factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis
by: Kong, Wei Yang
Published: (2019)

Zebularine and Trichostatin A sensitised human breast adenocarcinoma cells towards tumour necrosis factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis
by: Kong, Wei Yang, et al.
Published: (2019)

Accelerated carcinogenesis of colorectal cancer
by: Lam, XiuQian
Published: (2021)

Prognostic significance of Glutamine-Related Solute Carriers in luminal breast cancer
by: Erkan, Busra
Published: (2025)

Zerumbone and small interference RNA induced apoptosis in MCF-7 cell and mammary gland tumor via β-catenin protein inhibition
by: Fadl, Safa Abd Elfatah Amin
Published: (2013)

Induction of apoptosis by Elephantopus scaber L. ethanolic extract and effects of its interaction with tamoxifen on human breast cancer MCF-7 spheroids
by: Ho, Wan Yong
Published: (2012)

Effects of ampelopsin E towards the invasiveness of triple negative breast cancer cell line, MDA-MB-231
by: Tieng, Francis Yew Fu
Published: (2019)

The use of agonistic anti-CD40 therapy in treatments for cancer
by: Khong, A., et al.
Published: (2012)

Investigation of Cten signalling and regulation in colorectal cancer
by: Akhlaq, Maham
Published: (2016)

Design and Development of a Trailed Type Transplanter for Oil Palm Seedling
by: El Pebrian, Darius
Published: (2002)

Effects of silencing dishevelled 1, 2 and 3 mRNA expression on MDA-MB-231 cell migration and invasion using siRNAs
by: Khoo, Samuel Leon Juan
Published: (2015)

Mitotic activity of survivin is regulated by acetylation at K129
by: Aljaberi, Aysha M., et al.
Published: (2015)

The functional repertoire of survivin's tails
by: Wheatley, Sally P.
Published: (2015)

Targeted abrogation of diverse signal transduction cascades by emodin for the treatment of inflammatory disorders and cancer
by: Shrimali, D., et al.
Published: (2013)

Effect of gamma-oryzanol, oryzanol rich fraction and fractioned components on colorectal cancer cell line (HT-29) and cytokine production by human peripheral blood mononuclear cells
by: Alishavandi, Sima
Published: (2011)

Characterization and cytotoxicity of clausenidin from Clausena excavata Burm f. and its effects on cell cycle regulation and apoptosis of liver (hepg2) and colon (ht29) cancer cell lines
by: Waziri, Peter Maitalata
Published: (2017)

Protein Kinase C-Delta C2 Domain Interactions in Breast Cancer
by: Khader, Rasha
Published: (2023)

Secreted Frizzled-Related Protein 4 expression is positively associated with responsiveness to Cisplatin of ovarian cancer cell lines in vitro and with lower tumour grade in mucinous ovarian cancers
by: Saran, U., et al.
Published: (2012)

Spectrum of autoantibody response to tumour associated antigens in normal population
by: Mathew, John
Published: (2013)

Identification of drug(s) selectively targeting colorectal cancer stem-like cells for differentiation (differentiation therapy)
by: Ahmed, Mehreen
Published: (2020)

Serum autoantibodies as tumour markers in breast cancer: their role in screening, diagnosis and prognosis
by: Khan, Hamed N.
Published: (2009)

Recurrent paediatric ependymoma: a multicentre analysis of clinical features and tumour biology in the molecular era
by: Ritzmann, Timothy
Published: (2018)

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins
by: Subramaniam, Aruljothi, et al.
Published: (2013)

Finding chemo: the search for marine-based pharmaceutical drugs active against cancer
by: Indumathy, S., et al.
Published: (2013)

In vitro growth inhibition, molecular mechanisms of cell cycle arrest, and apoptosis in prostate cancer cells by SRJ23
by: Wong, Hui Chyn
Published: (2013)

Physical impact indicators for mountain trails at Gunung Tahan Trail, Malaysia
by: Yaakob, Sam Shor Nahar
Published: (2019)

Role and regulation of CTEN in colorectal cancer
by: Alfahed, Abdulaziz/AF
Published: (2020)

Generation and characterisation of adipose tissue-and umbilical-cord-derived mesenchymal stem cells expressing trail apoptotic ligand
by: Shamsul Kamal, Aishah Amirah
Published: (2024)