QR Code

Interrogating the genetic profile of sporadic colorectal cancer

Background and aims: Colorectal cancer (CRC) is one of the most common types of cancers. Prognosis for CRC is dependent on the stage of the disease at diagnosis and a variety of molecular features including expression of biomarkers and gene mutation. This study sought to (i) develop molecular tests...

Full description

Bibliographic Details
Main Author:	Fadhil, Wakkas M.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2019
Subjects:	Colorectal cancer; Biomarkers; Gene mutation
Online Access:	https://eprints.nottingham.ac.uk/59487/

Similar Items

Investigating the interactions between tumour cells and the non-tumour cellular community in colorectal cancer
by: Susanti, Susanti
Published: (2021)

Expression of β-catenin, Ki67 and stroma percentage in colorectal cancer
by: Suanno, Cristina
Published: (2021)

Molecular characterisation of the early metastatic phenotype in colorectal cancer
by: Sculthorpe, Declan
Published: (2024)

Accelerated carcinogenesis of colorectal cancer
by: Lam, XiuQian
Published: (2021)

An investigation of chromosome 20q13 amplification in colorectal cancer
by: Al-masmoum, Hussain
Published: (2016)

Elucidating the interactions between the adhesive and transcriptioanl functions of beta-catenin in normal and cancerous cells
by: van Leeuwen, Ingeborg M. M., et al.
Published: (2007)

DNA content analysis of colorectal cancer defines a distinct ‘microsatellite and chromosome stable’ group but does not predict response to radiotherapy
by: Fadhil, Wakkas, et al.
Published: (2014)

Surgical resection of primary tumour improves aerobic performance in colorectal cancer
by: Williams, John P., et al.
Published: (2014)

Investigate tumour heterogeneity and genetic pathways in colorectal cancer
by: Ham Karim, Hersh Abdul
Published: (2017)

Investigating the role of Cten in metastatic colorectal cancer
by: Thorpe, Hannah
Published: (2016)

Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England
by: Walker, A.J., et al.
Published: (2014)

Human rather than mouse mesenchymal stem cells in 3D co-culture models boost proliferative and migratory characteristics of colorectal cancer cells through paracrine signalling pathways, highlighting species disconnects
by: Lu, M.
Published: (2022)

Role of CD133 in colorectal cancer
by: Ahmed, Tarek Mohamed Abdel Moneim Mohamed Elsaba
Published: (2011)

Systematic review of pre-operative exercise in colorectal cancer patients
by: Boereboom, C., et al.
Published: (2016)

Creatinine and myoglobin are poor predictors of anaerobic threshold in colorectal cancer and health
by: Nyasavajjala, Sitaramachandra M., et al.
Published: (2015)

Mechanisms and roles of FLYWCH1 in colorectal cancer
by: Onyido, Emenike K.
Published: (2017)

Cost-Effectiveness of an Advance Notification Letter to Increase Colorectal Cancer Screening
by: Cronin, P., et al.
Published: (2013)

CD10 inhibits cell motility but expression is associated with advanced stage disease in colorectal cancer
by: Raposo, T.P., et al.
Published: (2018)

A Comparison of Continuum and Cell-based Models of Colorectal Cancer
by: Walter, Alexander
Published: (2009)

Tea, Coffee, and Milk Consumption and Colorectal Cancer Risk
by: Green, C., et al.
Published: (2014)

Role and regulation of CTEN in colorectal cancer
by: Alfahed, Abdulaziz/AF
Published: (2020)

Studies using the anti-idiotypic monoclonal antibody 105AD7 in patients with advanced and primary colorectal cancer
by: Maxwell-Armstrong, Charles Alan
Published: (1998)

Outcomes in patients undergoing urgent colorectal surgery
by: Teloken, P., et al.
Published: (2014)

One-third of patients fail to return to work 1 year after surgery for colorectal cancer
by: Bhalla, Ashish, et al.
Published: (2014)

eIF4A2 is a regulator of hypoxic translation and colorectal tumour cell survival
by: Bolland, Hannah
Published: (2020)

Tissue resident CD8 T cells subsets: prognostic significance in colorectal cancer
by: Talhouni, Shahd
Published: (2022)

Investigating the role of FOSL2 and JUND in the molecular adaptation to hypoxia in colorectal cancer
by: Potgieter, Tammy
Published: (2023)

Dietary patterns and other factors in relation to colorectal cancer risk in Tehran Province, Iran
by: Safari, Akram
Published: (2012)

Histopathological analysis of CD44 and c-Myc in colorectal cancer
by: Littlewood, Stephanie
Published: (2021)

Combinatorial application of tocotrienols and chemotherapeutic drugs enhances apoptosis and autophagy in colorectal cancer cells
by: Tham, Shiau Ying
Published: (2020)

GENE NETWORKS CONTROLLING ANTHER TAPETUM DEVELOPMENT IN BARLEY (Hordeum vulgare) DURING EARLY ANTHER DEVELOPMENT
by: HUA, Miaoyuan
Published: (2021)

SPACA3gene variants in a New Zealand cohort of infertile and fertile couples
by: Prendergast, Deborah, et al.
Published: (2014)

N_LyST: a simple and rapid screening test for Lynch Syndrome
by: Susanti, Susanti, et al.
Published: (2018)

Development and validation of risk prediction equations to estimate survival in patients with colorectal cancer: cohort study
by: Hippisley-Cox, Julia, et al.
Published: (2017)

Netrin-1 as a potential target for metastatic cancer: focus on colorectal cancer
by: Ko, S., et al.
Published: (2014)

Determining the feasibility and effectiveness of high intensity interval training in preoperative colorectal cancer patients
by: Boereboom, Catherine L.
Published: (2017)

Optimisation of Faecal Immunochemical Test (FIT) for symptomatic colorectal cancer diagnosis
by: Bailey, James Alexander
Published: (2024)

Genetic screens in intestinal organoid (mini-gut) culture using CRISPR-Cas-9 System and studying the role of FBXL5 in colorectal cancer cells
by: Jinks, Nicholas
Published: (2022)

Advice to consult a general medical practitioner in Western Australia: could it be cancer?
by: Jiwa, Moyez, et al.
Published: (2009)

Colorectal cancer – applying a gender lens
by: Oberoi, Devesh, et al.
Published: (2014)