Rational design, synthesis and in vitro antimicrobial activity of teixobactin analogues
The recent discovery of teixobactin, a depsipeptide comprising a linear heptapeptide chain that is tethered to a 13-membered macrocyclic ring, has brought great promise of addressing the global issue of antimicrobial resistance. By binding to vital bacterial cell wall precursors known as lipid II an...
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| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2019
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| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/59235/ |
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