Examining the importance of survivin phosphorylation at Threonine 5 through its relationship with the kinase, TBK1, and the substrate, c-Src
As a protein that is significantly involved in many processes of cellular life and death, survivin has garnered much interest as a cancer-associated protein. It is the fourth most upregulated transcript in human cancers and it cooperates with several other proteins to aid oncogenesis. One of these i...
| Main Author: | Lishak, Jamie |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2019
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/59219/ |
Similar Items
Investigating the relationship between Survivin and Tank-Binding Kinase 1 in cancer cells
by: Daly, Lauren
Published: (2021)
by: Daly, Lauren
Published: (2021)
The N-terminus of survivin is a mitochondrial-targeting sequence and Src regulator
by: Dunajova, Lucia, et al.
Published: (2016)
by: Dunajova, Lucia, et al.
Published: (2016)
Mitogen-activated protein/extracellular signal-regulated kinase kinase 1act/tubulin interaction is an important determinant of mitotic stability in cultured HT1080 human fibrosarcoma cells.
by: Cao, Jia-ning, et al.
Published: (2010)
by: Cao, Jia-ning, et al.
Published: (2010)
Survivin and AURKA, key determinants of mitotic cell fate
by: Abdelkabir, Hana
Published: (2024)
by: Abdelkabir, Hana
Published: (2024)
Protein Kinase C-Delta C2 Domain Interactions in Breast Cancer
by: Khader, Rasha
Published: (2023)
by: Khader, Rasha
Published: (2023)
Mitotic activity of survivin is regulated by acetylation at K129
by: Aljaberi, Aysha M., et al.
Published: (2015)
by: Aljaberi, Aysha M., et al.
Published: (2015)
The functional repertoire of survivin's tails
by: Wheatley, Sally P.
Published: (2015)
by: Wheatley, Sally P.
Published: (2015)
Cytokinesis is controlled by monomer-dimer switching of survivin
by: Zahim, Duaa
Published: (2024)
by: Zahim, Duaa
Published: (2024)
Evaluation of transcriptional cyclin dependent kinase inhibitors as potential cancer therapeutics
by: Liu, Xiangrui
Published: (2012)
by: Liu, Xiangrui
Published: (2012)
The response of survivin to hypoxia and the functional roles of its subcellular pools.
by: Fezovich, Alexander
Published: (2023)
by: Fezovich, Alexander
Published: (2023)
Comparative study on mitogen activated protein kinase of Plasmodium species by using in silico method / Mohd Fakharul Zaman Raja Yahya and Hasidah Mohd Sidek
by: Raja Yahya, Mohd Fakharul Zaman, et al.
Published: (2012)
by: Raja Yahya, Mohd Fakharul Zaman, et al.
Published: (2012)
Identification of novel survivin interactors
by: Alhawsawi, Naif
Published: (2024)
by: Alhawsawi, Naif
Published: (2024)
Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer
by: Aljaberi, Aysha M., et al.
Published: (2014)
by: Aljaberi, Aysha M., et al.
Published: (2014)
The role of survivin in autophagy
by: Humphry, Nicola
Published: (2018)
by: Humphry, Nicola
Published: (2018)
Investigating how survivin expression affects the cell death response induced by UV irradiation
by: Coe, Kirstie Danielle
Published: (2020)
by: Coe, Kirstie Danielle
Published: (2020)
Phosphorylation of the PKG substrate, vasodilator-stimulated phosphoprotein (VASP), in human cultured prostatic stromal cells
by: Cook, Anna, et al.
Published: (2007)
by: Cook, Anna, et al.
Published: (2007)
Aggregation Prone Region analogues: synthetic excipients for protein formulation
by: Foralosso, Ruggero
Published: (2019)
by: Foralosso, Ruggero
Published: (2019)
Emerging role of the KRAS-PDK1 axis in pancreatic cancer
by: Ferro, R., et al.
Published: (2014)
by: Ferro, R., et al.
Published: (2014)
Investigating a key autophagy protein-protein interaction and its modulation by phosphorylation and an ALS-related mutation
by: Brennan, Andrew
Published: (2019)
by: Brennan, Andrew
Published: (2019)
Increases in intracellular calcium perturb blood–brain barrier via protein kinase C-alpha and apoptosis
by: Rakkar, Kamini, et al.
Published: (2016)
by: Rakkar, Kamini, et al.
Published: (2016)
Impacts of Temperature-Induced Change of Formulation Buffers on the Stability of Proteins in Solution
by: Jeluk, Aimée
Published: (2025)
by: Jeluk, Aimée
Published: (2025)
Compartmentalised signalling and trafficking of CXCR4 and ACKR3
by: Karsai, Noemi
Published: (2025)
by: Karsai, Noemi
Published: (2025)
Elucidating the role of Cdk13 and Prkd1 in heart development and congenital heart disease
by: Waheed Ullah, Qazi
Published: (2024)
by: Waheed Ullah, Qazi
Published: (2024)
Functional analysis of the group specific interactions between AIP and AgrC in Staphylococcus aureus
by: Jensen, Rasmus O.
Published: (2009)
by: Jensen, Rasmus O.
Published: (2009)
Low molecular weight nucleoside gelator: A novel approach for protein and peptide aggregation inhibition
by: Johnson, Litty
Published: (2019)
by: Johnson, Litty
Published: (2019)
Impact of p38 mitogen-activated protein kinase inhibition on immunostimulatory properties of human 6-sulfo LacNAc dendritic cells
by: Langosch, Saskia, et al.
Published: (2016)
by: Langosch, Saskia, et al.
Published: (2016)
Conformational design of minilipase
by: Baharum, Hafidza
Published: (2013)
by: Baharum, Hafidza
Published: (2013)
Clinicopathological and prognostic significance of mitogen-activated protein kinases (MAPK) in breast cancers
by: Ahmad, Dena Akram Jerjees, et al.
Published: (2016)
by: Ahmad, Dena Akram Jerjees, et al.
Published: (2016)
The Mak2 MAP kinase signal transduction pathway is required for pathogenicity in Stagonospora nodorum
by: Solomon, P., et al.
Published: (2005)
by: Solomon, P., et al.
Published: (2005)
Inhibition of HOX/PBX dimer formation leads to necroptosis in acute myeloid leukemia cells
by: Alharbi, Raed A., et al.
Published: (2017)
by: Alharbi, Raed A., et al.
Published: (2017)
Divergence of intracellular and extracellular HSP72 in type 2 diabetes: does fat matter?
by: Rodrigues-Krause, J., et al.
Published: (2012)
by: Rodrigues-Krause, J., et al.
Published: (2012)
Protein Structure-Based Design of Novel Semisynthetic Metallotrypsin
by: Misran, Azizah
Published: (2006)
by: Misran, Azizah
Published: (2006)
Structural investigation of alcohol oxidase from Meyerozyma guilliermondii and the use of its promoter for recombinant protein expression
by: Mahyon, Nur Iznida
Published: (2017)
by: Mahyon, Nur Iznida
Published: (2017)
Protein-Solvent Interaction of Thermostable Lipase for Biocatalysis in Organic Solvents
by: Tengku Abdul Hamid, Tengku Haziyamin
Published: (2009)
by: Tengku Abdul Hamid, Tengku Haziyamin
Published: (2009)
Molecular dynamics simulation of the phosphorylation-induced conformational changes of a tau peptide fragment
by: Lyons, Albert, et al.
Published: (2014)
by: Lyons, Albert, et al.
Published: (2014)
Truncated chicken anemia virus-VP3 as a potential anti tumour vaccine
by: Lim, Shen Ni
Published: (2012)
by: Lim, Shen Ni
Published: (2012)
Advances in protein ontology project
by: Sidhu, Amandeep, et al.
Published: (2006)
by: Sidhu, Amandeep, et al.
Published: (2006)
Discovery of highly potent and selective phosphatidylinositol 3-kinase-δ inhibitors for the treatment of blood cancers and autoimmune diseases
by: Buzrieda, Anas
Published: (2021)
by: Buzrieda, Anas
Published: (2021)
Automated design of energy functions for protein structure prediction by means of genetic programming and improved structure similarity assessment
by: Widera, Paweł
Published: (2010)
by: Widera, Paweł
Published: (2010)
Regulation of human heterochromatin protein 1 binding protein 3 (HP1BP3, also known as HP1BP74) in response to the DNA damage
by: Normatova, Makhliyo
Published: (2016)
by: Normatova, Makhliyo
Published: (2016)
Similar Items
-
Investigating the relationship between Survivin and Tank-Binding Kinase 1 in cancer cells
by: Daly, Lauren
Published: (2021) -
The N-terminus of survivin is a mitochondrial-targeting sequence and Src regulator
by: Dunajova, Lucia, et al.
Published: (2016) -
Mitogen-activated protein/extracellular signal-regulated kinase kinase 1act/tubulin interaction is an important determinant of mitotic stability in cultured HT1080 human fibrosarcoma cells.
by: Cao, Jia-ning, et al.
Published: (2010) -
Survivin and AURKA, key determinants of mitotic cell fate
by: Abdelkabir, Hana
Published: (2024) -
Protein Kinase C-Delta C2 Domain Interactions in Breast Cancer
by: Khader, Rasha
Published: (2023)