Investigating the effect of N-terminal methionine addition, hydrophobic interaction enhancement and loop modification in modifying immunomodulatory and cancer-inhibitory activities of FIP-fve mutants

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Investigating the effect of N-terminal methionine addition, hydrophobic interaction enhancement and loop modification in modifying immunomodulatory and cancer-inhibitory activities of FIP-fve mutants

FIP-fve is an immunomodulatory protein isolated from edible enokitake mushroom Flammulina velutipes and grouped under fungal immunomodulatory proteins (FIPs) family. FIPs are well documented for their immunomodulation, anti-allergy and anti-tumour activities. Herein, this study is motivated by a lac...

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Bibliographic Details
Main Author:	Chan, Won Ting
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2019
Subjects:	FIP-fve flammulina velutipes fungal immunomodulatory protein protein engineering
Online Access:	https://eprints.nottingham.ac.uk/56878/

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