Synthesis and Biological Evaluation of Novel Imidazotetrazines

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Synthesis and Biological Evaluation of Novel Imidazotetrazines

Glioblastoma Multiforme (GBM) is the most prevalent form of primary brain tumour in adults and is very fast growing. Current treatment involves surgery, radiotherapy and chemotherapy with the alkylating agent temozolomide (TMZ; 1), however innate and acquired resistance often develop after initial T...

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Bibliographic Details
Main Author:	Summers, Helen S
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2019
Subjects:	brain tumours Glioblastoma Multiforme GBM Alkylating agents
Online Access:	https://eprints.nottingham.ac.uk/56789/

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