Synthesis and Biological Evaluation of Novel Imidazotetrazines
Glioblastoma Multiforme (GBM) is the most prevalent form of primary brain tumour in adults and is very fast growing. Current treatment involves surgery, radiotherapy and chemotherapy with the alkylating agent temozolomide (TMZ; 1), however innate and acquired resistance often develop after initial T...
| Main Author: | |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2019
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/56789/ |