Modulation of IL-10 production by CD3/CD55 induced Type 1 regulatory (Tr1) T-cells

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Modulation of IL-10 production by CD3/CD55 induced Type 1 regulatory (Tr1) T-cells

A healthy immune system is maintained in a state of balance between pro-inflammatory and anti-inflammatory cells. The paradigm for T-cell activation requires CD80/86:CD28 engagement resulting in differentiation of CD4+ T-helper cells. However, alternative costimulatory molecules may favour the induc...

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Bibliographic Details
Main Author:	Musarrat, Tajkia
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2019
Subjects:	IL-10 Tr1 cells CD55
Online Access:	https://eprints.nottingham.ac.uk/56736/

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