Analysis of candidate retinal autoantigens in autoimmune uveitis

QR Code

Analysis of candidate retinal autoantigens in autoimmune uveitis

Autoimmune uveitis is a non-infective ocular inflammation of humans that potentially causes blindness. It is mediated primarily by autoreactive CD4+ Tlymphocytes that target antigens within the retina. Autoantibody responses play a secondary role. This thesis describes various investigations into hu...

Full description

Bibliographic Details
Main Author:	Morgan, James
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2005
Subjects:	Uveitis; Cellular immune responses; Recombinant human retinal S antigen; Autoantigenic peptides; Cytokine profiles
Online Access:	https://eprints.nottingham.ac.uk/56713/

Similar Items

Investigation of the epitope specificities of antibodies to islet β-cell autoantigens
by: Al-bukhari, Talat Abdullah
Published: (2001)

Cytokine gene expression patterns and immune responses to systemic Candida albicans infection in inbred mice.
by: Redwood, Alec J.
Published: (1997)

Immune Cells Function and Activation in Response to Carica Papaya L. Consumed by Healthy Individuals
by: Loh, Chiew Yee
Published: (2011)

Autoantibodies of IgM and IgG classes show differences in recognition of multiple autoantigens in chronic obstructive pulmonary disease
by: Shindi, Reham, et al.
Published: (2017)

Development of secretory expression system using synthetic signal peptides spA and spD for protein production in Escherichia coli.
by: Velaithan, Vithya
Published: (2011)

Label-free Raman hyperspectral imaging of single cells cultured on polymer substrates
by: Sinjab, Faris, et al.
Published: (2017)

Selection of high affinity ligands to hepatitis B core antigen from a phage-displayed cyclic peptide library.
by: Ho, Kok Lian, et al.
Published: (2003)

Risk for Retinal Detachment After Phacoemulsification: A Whole-Population Study of Cataract Surgery Outcomes
by: Clark, Antony, et al.
Published: (2012)

Natural T cell–mediated protection against seasonal and pandemic Influenza: results of the Flu Watch cohort study
by: Hayward, Andrew C., et al.
Published: (2015)

Bacterial biofilm interactions with human immune cells
by: Lee, Kelly
Published: (2023)

The expression of HLA class I molecules and complement regulatory proteins in ovarian cancer
by: Rolland, Philip
Published: (2008)

Characterisation of erythropoietin gene-modified human mesenchymal stem cells and anti-apoptotic effect of glutamate excitotoxicity in a retinal neuron cell line
by: Shirley, Ding Suet Lee
Published: (2017)

The identification of targeting peptides and tumour associated antigens for the treatment and early detection of triple negative breast cancer
by: Wilde, Megan
Published: (2023)

The mechanism of age-related immunity in cattle
by: Sharma, Parul
Published: (2019)

Edge detection of the optic disc in retinal images based on identification of a round shape
by: Chaichana, T., et al.
Published: (2008)

Molecular and cellular analysis of MSC-EPO-mediated protection of degenerating retinas
by: Koh, Avin Ee Hwan
Published: (2021)

Transcriptome profile of the human endothelial cell response to high- and low-density infections of Candida albicans
by: Chong, Pei Pei, et al.
Published: (2010)

Assessment of intestinal immunity development in juvenile tiger grouper, Epinephelus fuscoguttatus (Forsskal, 1775) following oral exposure to Bioencapsulated vibriosis vaccine
by: Nawi, Mohd Firdaus
Published: (2017)

Immune modulatory properties of nanoparticles on human dendritic cells
by: Al-Zahri, Reem
Published: (2018)

Multiplexed antigen microarray development for comprehensive immune health profiling: a proof of concept study
by: Thompson, Chloe
Published: (2024)

Carbohydrate-mediated antigenic cross-reactivity between Schistosoma mansoni antigens and environmental allergens
by: Gai, Fatou
Published: (2020)

The ecology of immune variation in wild house mice (Mus musculus domesticus)
by: Young, Stuart
Published: (2019)

Host defence peptide (HDP) human beta defensin 9 (HBD9)
by: Omar, Nazri
Published: (2016)

Immunization with a DNA vaccine cocktail encoding TgPF, TgROP16, TgROP18, TgMIC6, and TgCDPK3 genes protects mice against chronic toxoplasmosis
by: Zhang, Nian-Zhang, et al.
Published: (2018)

An investigation of the epidemiology of age-related maculopathy in the UK
by: Wilde, Craig
Published: (2018)

Characterisation of the modulation of immune response to polymer implants using established and novel methods
by: Suvannapruk, Waraporn
Published: (2023)

A model of persistent Salmonella infection: Salmonella pullorum modulates the immune response of the chicken from a Th17 towards a Th2-type response
by: Tnag, Ying, et al.
Published: (2018)

Development of murine immune responses to H5 DNA vaccine with IRF3 as genetic adjuvant and HIV Tat-conjugated pamam dendrimer as the delivery system
by: Bahadoran, Azadeh
Published: (2016)

The impact of stroma and ionising radiation on the plasticity of dendritic cells and macrophages
by: Malecka, Anna A.
Published: (2018)

Visual contrast detection cannot be predicted from surrogate measures of retinal ganglion cell number and sampling density in healthy young adults
by: Denniss, Jonathan, et al.
Published: (2014)

Photocatalytic Tryptophan Alkylation for Chemoselective Peptide Modification
by: Lee, Joanna
Published: (2024)

Prevalence and genetic analyses of selected age-related macular degeneration-related polymorphisms and their responses to intravitreal ranibizumab
by: Mohamad, Nur Afiqah
Published: (2018)

Factors influencing the removal of immune complex deposits from the renal glomerulus
by: Furness, Peter Norman
Published: (1988)

Detection of glaucoma in the elderly using laser scanning tomography
by: Hawker, Matthew James
Published: (2008)

Inflammation-mediated muscle metabolic dysregulation local and remote to the site of major abdominal surgery
by: Varadhan, Krishna K., et al.
Published: (2017)

Exploiting the plasticity of primary and secondary response mechanisms in artificial immune systems
by: Greensmith, Julie, et al.
Published: (2016)

Palm oil γ-tocotrienol and α-tocopherol act as potent inducers in the immune response of mouse splenocytes in vitro / Narimah Abdul Hamid Hasani, Khalid bin Abdul Kadir and Wan Zurinah Wan Ngah
by: Abdul Hamid Hasani, Narimah, et al.
Published: (2011)

Cytotoxic T-Lymphotyces antigen 4 gene polymorphism and cytokine levels among severe haemophilia a patients with and without inhibitors
by: Nadarajan, Anantha Kummar
Published: (2020)

Production of Hepatitis B Viral Antigens and Antibodies using Phage Display Technology for the Development of a Diagnostic Test
by: Tan, Geok Hun
Published: (2006)

Pan-cancer vaccines: breaking tolerance by targeting stress-induced post-translational modifications in tumours
by: Atabani, Suha
Published: (2023)